Results 31 to 40 of about 1,605,623 (291)
Exosomes released from breast cancer carcinomas stimulate cell movement [PDF]
, 2015 For metastasis to occur cells must communicate with to their local environment to initiate growth and invasion. Exosomes have emerged as an important mediator of cell-to-cell signalling through the transfer of molecules such as mRNAs, microRNAs, and ...
Gucek, Marjan +5 more
core +4 more sources
SUMO wrestling in cell movement [PDF]
Cell Research, 2010 Small ubiquitin-like modifier (SUMO) proteins 1, 2 and 3 can be covalently conjugated to specific lysine residues on target proteins in a process dubbed SUMOylation. This conserved posttranslational modification that was reported for the first time in 1996 has emerged as an important regulatory mechanism in cell physiology, especially in nuclear ...
Miia M, Rytinki, Jorma J, Palvimo
openaire +2 more sources
Effect of protein kinase N1 on the biological behavior of human glioma
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Objective To study the expression of protein kinase N1 (PKN1) in glioma and its influence on the biological behavior of glioma cells. Methods The expression of PKN1 gene was verified via GEPIA database, and LN229, U87 and A172 gliomas cells were detected
Yu⁃bing HAO +5 more
doaj
Cancer Biology & Medicine, 2010 OBJECTIVE Hepatocyte growth factor (HGF) expression is closely related to the progression and poor prognosis of colorectal cancer patients. In this study, we investigated the effects on proliferation and migration of the human colon carcinoma cell line ...
Wei GUO +6 more
doaj +1 more source
TRPM7 regulates polarized cell movements [PDF]
Biochemical Journal, 2011 TRPM7 (transient receptor potential melastatin 7) is a Ca2+- and Mg2+-permeant ion channel in possession of its own kinase domain. As a kinase, the protein has been linked to the control of actomyosin contractility, whereas the channel has been found to regulate cell adhesion as well as cellular Mg2+ homoeostasis.
Li-Ting, Su +5 more
openaire +2 more sources
Development of a Computational Model for Cell Activity in a Nano-Scaffold [PDF]
, 2020 Tissue engineering utilizes nano-scaffolds to direct cell growth and control cell behavior. Since cells occupy specific spaces within extracellular matrix (ECM) it’s important to understand how the geometry of these spaces influence cell behaviors such ...
Babcock, Ethan, Luke, Bethany
core +1 more source
Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]
, 2011 The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
A Cvejic +52 more
core +8 more sources
Frontiers in Bioinformatics, 2022 Malaria is a disease caused by Plasmodium parasites, resulting in over 200 million infections and 400,000 deaths every year. A critical step of malaria infection is when sporozoites, injected by mosquitoes, travel to the liver and form liver stages ...
Viktor S. Zenkov +5 more
doaj +1 more source
Mapping the Response of Human Osteocytes in Native Matrix to Mechanical Loading Using RNA Sequencing
JBMR Plus, 2023 Osteocytes sense mechanical loads and transduce mechanical signals into a chemical response. They are the most abundant bone cells deeply embedded in mineralized bone matrix, which affects their regulatory activity in the mechanical adaptation of bone ...
Chen Zhang +6 more
doaj +1 more source
Optimal cellular mobility for synchronization arising from the gradual recovery of intercellular interactions [PDF]
, 2012 Cell movement and intercellular signaling occur simultaneously during the development of tissues, but little is known about how movement affects signaling.
Andrew C Oates +5 more
core +2 more sources