Adult skeletal muscle stem cell migration is mediated by a blebbing/amoeboid mechanism [PDF]
Adult skeletal muscle possesses a resident stem cell population called satellite cells which are responsible for tissue repair following damage. Satellite cell migration is crucial in promoting rapid tissue regeneration but is a poorly understood ...
Collins-Hooper, Henry +4 more
core +1 more source
Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins. [PDF]
Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene ...
Bae, Hanhong +10 more
core +2 more sources
Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner
Hyperleptinemia, associated with obesity, is related with immune dysfunction and carcinogenesis. Natural Killer (NK) cells, a major component of the innate immune system are mediators of anti-tumor immunity and the most actively migrating cells among ...
Jana Oswald +5 more
doaj +1 more source
Exosomes released from breast cancer carcinomas stimulate cell movement [PDF]
For metastasis to occur cells must communicate with to their local environment to initiate growth and invasion. Exosomes have emerged as an important mediator of cell-to-cell signalling through the transfer of molecules such as mRNAs, microRNAs, and ...
Gucek, Marjan +5 more
core +4 more sources
Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]
The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
A Cvejic +52 more
core +8 more sources
SUMO wrestling in cell movement [PDF]
Small ubiquitin-like modifier (SUMO) proteins 1, 2 and 3 can be covalently conjugated to specific lysine residues on target proteins in a process dubbed SUMOylation. This conserved posttranslational modification that was reported for the first time in 1996 has emerged as an important regulatory mechanism in cell physiology, especially in nuclear ...
Miia M, Rytinki, Jorma J, Palvimo
openaire +2 more sources
OBJECTIVE Hepatocyte growth factor (HGF) expression is closely related to the progression and poor prognosis of colorectal cancer patients. In this study, we investigated the effects on proliferation and migration of the human colon carcinoma cell line ...
Wei GUO +6 more
doaj +1 more source
Development of a Computational Model for Cell Activity in a Nano-Scaffold [PDF]
Tissue engineering utilizes nano-scaffolds to direct cell growth and control cell behavior. Since cells occupy specific spaces within extracellular matrix (ECM) it’s important to understand how the geometry of these spaces influence cell behaviors such ...
Babcock, Ethan, Luke, Bethany
core +1 more source
Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells [PDF]
There are cells acattered in the rear, prespore region of the Dictyostelium slug that share many of the properties of the prestalk cells and that are therefore called anterior-like cells (ALCs).
Akiyama +41 more
core +1 more source
TRPM7 regulates polarized cell movements [PDF]
TRPM7 (transient receptor potential melastatin 7) is a Ca2+- and Mg2+-permeant ion channel in possession of its own kinase domain. As a kinase, the protein has been linked to the control of actomyosin contractility, whereas the channel has been found to regulate cell adhesion as well as cellular Mg2+ homoeostasis.
Li-Ting, Su +5 more
openaire +2 more sources

