Results 41 to 50 of about 1,482,013 (279)

Mapping the Response of Human Osteocytes in Native Matrix to Mechanical Loading Using RNA Sequencing

JBMR Plus, 2023
Osteocytes sense mechanical loads and transduce mechanical signals into a chemical response. They are the most abundant bone cells deeply embedded in mineralized bone matrix, which affects their regulatory activity in the mechanical adaptation of bone ...
Chen Zhang, Huib W. vanEssen, Daoud Sie, Dimitra Micha, Gerard Pals, Jenneke Klein‐Nulend, Nathalie Bravenboer   +6 more
doaj   +1 more source

Emergence of collective propulsion through cell-cell adhesion

, 2017
The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in collective cell ...
Matsushita, Katsuyoshi
core   +1 more source

Kappa-carrageenan-Functionalization of octacalcium phosphate-coated titanium Discs enhances pre-osteoblast behavior and osteogenic differentiation

Frontiers in Bioengineering and Biotechnology, 2022
Bioactive coatings are promising for improving osseointegration and the long-term success of titanium dental or orthopaedic implants. Biomimetic octacalcium phosphate (OCP) coating can be used as a carrier for osteoinductive agents.
Wei Cao, Wei Cao, Jianfeng Jin, Gang Wu, Nathalie Bravenboer, Marco N. Helder, Engelbert A. J. M. Schulten, Rommel G. Bacabac, Janak L. Pathak, Jenneke Klein-Nulend   +9 more
doaj   +1 more source

Quantitative imaging of the collective cell movements shaping an embryo [PDF]

, 2009
The recent development of imaging and image processing techniques, such as 4D microscopy and 3D cell tracking, enables analysis through quantification of the movement of large cell populations in vivo.
Fraser, Scott E., McMahon, Amy, Stathopoulos, Angelike, Supatto, Willy   +3 more
core   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Cortical Factor Feedback Model for Cellular Locomotion and Cytofission [PDF]

, 2009
Eukaryotic cells can move spontaneously without being guided by external cues. For such spontaneous movements, a variety of different modes have been observed, including the amoeboid-like locomotion with protrusion of multiple pseudopods, the keratocyte ...
A Nagasaki, A Stéphanou, A Stéphanou, AB Verkhovsky, AFM Marée, B Rubinstein, C Janetopoulos, C Jiménez, CA Parent, CA Parent, D Bottino, D Bray, D Wessels, E Caron, EE Sander, FN Fan Leeuwen, GCM Zondag, I Weber, J Dai, J Lee, J Lenz, J Satulovsky, JA Glazier, JA Spudich, K Keren, K Suzuki, L Haviv, L Yang, M Ueda, Masahiro Ueda, Masaki Sasai, P Dieterich, Philip E. Bourne, R Neujahr, RA Firtel, RNC Heizer, S Yumura, Shin I. Nishimura, SI Nishimura, SI Nishimura, SVM Satyanarayana, TD Pollard, TD Pollard, TQP Uyeda, W Alt, Y Asano   +45 more
core   +4 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Coordinated Morphogenetic Mechanisms Shape the Vertebrate Eye

Frontiers in Neuroscience, 2017
The molecular bases of vertebrate eye formation have been extensively investigated during the past 20 years. This has resulted in the definition of the backbone of the gene regulatory networks controlling the different steps of eye development and has ...
Juan-Ramon Martinez-Morales, Florencia Cavodeassi, Florencia Cavodeassi, Paola Bovolenta, Paola Bovolenta   +4 more
doaj   +1 more source

Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells [PDF]

, 1994
There are cells acattered in the rear, prespore region of the Dictyostelium slug that share many of the properties of the prestalk cells and that are therefore called anterior-like cells (ALCs).
Akiyama, Blaschke, Bonner, Bonner, Buhl, Ceccarelli, Chung, Devine, Early, Early, Early, Evan, Francis, Gaskell, Gregg, Gregg, Hadwiger, Harlow, Harwood, Howard, Jermyn, Jermyn, Kakutani, McRobbie, Montell, Niehrs, Nomura, Raper, Raper, Rubin, Salser, Siegert, Siegert, Siegert, Steinbock, Sternfeld, Sternfeld, Sternfeld, Takeuchi, Ti, Watts, Williams   +41 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source