Results 111 to 120 of about 827,170 (307)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Patch-clamp detection of macromolecular translocation along nuclear pores

Brazilian Journal of Medical and Biological Research, 1998
The present paper reviews the application of patch-clamp principles to the detection and measurement of macromolecular translocation along the nuclear pores.
Bustamante J.O., Varanda W.A.
doaj  

Characterization of Human Anulus Fibrosus– and Nucleus Pulposus–Derived Cells During Monolayer Expansion and in Hydrogel Cultures [PDF]

, 2014
Gundula Schulze‐Tanzil, Marion Lemke, Carola Meier, Wolfgang Ertel, Benjamin Kohl, Zhao Huang, M. Muschik, Markus Markart, Mariann Hoyer, Stephan Arens   +9 more
openalex   +1 more source

Single nucleus RNASeq profiling of mouse lung: reduced dissociation bias and improved detection of rare cell types compared with single cell RNASeq [PDF]

, 2020
Jeffrey R. Koenitzer, Hao Wu, Jeffrey J. Atkinson, Steven L. Brody, Benjamin D. Humphreys   +4 more
openalex   +1 more source

Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus. [PDF]

J Virol, 2023
Padron A, Prakash P, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C.   +6 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Classification of hyperspectral images for detection of hepatic carcinoma cells based on spectral–spatial features of nucleus

, 2019
Yao Chen, Siqi Zhu, Shenhe Fu, Zhen Li, Furong Huang, Hao Yin, Zhenqiang Chen   +6 more
openalex   +1 more source

Viscous shaping of the compliant cell nucleus. [PDF]

APL Bioeng, 2022
Dickinson RB, Katiyar A, Dubell CR, Lele TP.   +3 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source