Results 91 to 100 of about 6,341,201 (297)

Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat, Rhinolophus rouxi [PDF]

open access: yes, 1986
1. Horseradish peroxidase was applied by iontophoretic injections to physiologically identified regions of the laryngeal motor nucleus, the nucleus ambiguus in the CF/FM batRhinolophus rouxi. 2.
Rübsamen, R., Schweizer, Hermann
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Nuclear CaMKII Isoforms as Regulators of Transcription: From Developmental to Pathological Persistence

open access: yesMedical Sciences
Calcium/calmodulin-dependent protein kinase II (CaMKII) comprises multiple isoforms with distinct nuclear variants that exert transcriptional control in a context-dependent manner.
Areli Marlene Gaytán-Gómez   +16 more
doaj   +1 more source

Cell Injection Millirobot Development and Evaluation in Microfluidic Chip

open access: yesMicromachines, 2018
We propose an innovative design of millirobot, which can achieve donor cell suction, delivery, and injection in a mammalian oocyte on a microfluidic chip.
Lin Feng   +6 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

E-MEXP-2488 - Transcription profiling of human nucleus pulposus vs articular cartilage cell types

open access: yes, 2010
Human nucleus pulposus cell vs articular ...
Division of Cell Matrix Biology & Regenerative Medicine (L5)   +1 more
core   +1 more source

Pathways and mechanisms of transmembrane calcium ions exchange in the cell nucleus

open access: yes, 2018
A variety of nuclear calcium functions includes regulations of gene transcription and permeability of nuclear pore complexes, activation of numerous enzymes involved in the apoptosis, and therefore cell fate determination.
T. O. Veklich   +2 more
core   +1 more source

Cytoskeletal proteins in the cell nucleus : a special nuclear actin perspective [PDF]

open access: yes, 2019
The emerging role of cytoskeletal proteins in the cell nucleus has become a new frontier in cell biology. Actin and actin-binding proteins regulate chromatin and gene expression, but importantly they are beginning to be essential players in genome ...
Vartiainen, Maria   +2 more
core   +1 more source

Nucleus-Targeting Manganese Dioxide Nanoparticles Coated with the Human Umbilical Cord Mesenchymal Stem Cell Membrane for Cancer Cell Therapy

open access: yes, 2023
Recently, development of drug delivery systems for accurate delivery of antitumor drugs to tumor sites to improve their antitumor efficacy has attracted great interest in the area of cancer immunotherapy.
Mingyue Shao (14615733)   +11 more
core   +1 more source

Home - About - Disclaimer - Privacy