Results 71 to 80 of about 5,980,419 (302)

The role of vimentin–nuclear interactions in persistent cell motility through confined spaces

New Journal of Physics, 2021
The ability of cells to move through small spaces depends on the mechanical properties of the cellular cytoskeleton and on nuclear deformability. In mammalian cells, the cytoskeleton is composed of three interacting, semi-flexible polymer networks: actin,
Sarthak Gupta, Alison E Patteson, J M Schwarz   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat, Rhinolophus rouxi [PDF]

, 1986
1. Horseradish peroxidase was applied by iontophoretic injections to physiologically identified regions of the laryngeal motor nucleus, the nucleus ambiguus in the CF/FM batRhinolophus rouxi. 2.
Rübsamen, R., Schweizer, Hermann
core   +1 more source

The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity

Journal of Integrative Neuroscience
Background: In neuroscience, Ca2+ imaging is a prevalent technique used to infer neuronal electrical activity, often relying on optical signals recorded at low sampling rates (3 to 30 Hz) across multiple neurons simultaneously.
Katarina D. Milicevic, Violetta O. Ivanova, Tina N. Brazil, Cesar A. Varillas, Yan M.D. Zhu, Pavle R. Andjus, Srdjan D. Antic   +6 more
doaj   +1 more source

Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

European Journal of Histochemistry, 2015
Ozone therapy is a modestly invasive procedure based on the regeneration capabilities of low ozone concentrations and used in medicine as an alternative/adjuvant treatment for different diseases.
M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta   +6 more
doaj   +1 more source

Novel Scaffold Based on Chitosan Hydrogels/Phthalated Cashew Gum for Supporting Human Dental Pulp Stem Cells

Pharmaceuticals, 2023
Hydrogels are structures that have value for application in the area of tissue engineering because they mimic the extracellular matrix. Naturally obtained polysaccharides, such as chitosan (CH) and cashew gum, are materials with the ability to form ...
Yulla Klinger de Carvalho Leite, Antônia Carla de Jesus Oliveira, Patrick Veras Quelemes, Napoleão Martins Argolo Neto, Camila Ernanda Sousa de Carvalho, Huanna Waleska Soares Rodrigues, Michel Muálem de Moraes Alves, Fernando Aécio de Amorim Carvalho, Daniel Dias Rufino Arcanjo, Edson Cavalcanti da Silva-Filho, Alessandra Durazzo, Massimo Lucarini, Maria Acelina Martins de Carvalho, Durcilene Alves da Silva, José Roberto de Souza de Almeida Leite   +14 more
doaj   +1 more source

Spandrels of the cell nucleus

Current Opinion in Cell Biology
S.J. Gould and R. Lewontin in their famous "Spandrels paper" (1979) argued that many anatomical elements arise in evolution not due to their "current utility" but rather due to other "reasons for origin", such as other developmental processes, physical constraints and mechanical forces.
Irina Solovei, Leonid Mirny
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The sensitive period for the morphological effects of monocular deprivation in two nuclei of the tectofugal pathway of zebra finches [PDF]

, 1988
Herrmann K, Bischof H-J. The sensitive period for the morphological effects of monocular deprivation in two nuclei of the tectofugal pathway of zebra finches. Brain Research.
Herrmann, Kathrin, Bischof, Hans-Joachim
core   +1 more source