Results 61 to 70 of about 6,341,201 (297)

The Emerging Roles of Heterochromatin in Cell Migration

open access: yesFrontiers in Cell and Developmental Biology, 2020
Cell migration is a key process in health and disease. In the last decade an increasing attention is given to chromatin organization in migrating cells. In various types of cells induction of migration leads to a global increase in heterochromatin levels.
Gabi Gerlitz
doaj   +1 more source

The role of vimentin–nuclear interactions in persistent cell motility through confined spaces

open access: yesNew Journal of Physics, 2021
The ability of cells to move through small spaces depends on the mechanical properties of the cellular cytoskeleton and on nuclear deformability. In mammalian cells, the cytoskeleton is composed of three interacting, semi-flexible polymer networks: actin,
Sarthak Gupta   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity

open access: yesJournal of Integrative Neuroscience
Background: In neuroscience, Ca2+ imaging is a prevalent technique used to infer neuronal electrical activity, often relying on optical signals recorded at low sampling rates (3 to 30 Hz) across multiple neurons simultaneously.
Katarina D. Milicevic   +6 more
doaj   +1 more source

Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

open access: yesEuropean Journal of Histochemistry, 2015
Ozone therapy is a modestly invasive procedure based on the regeneration capabilities of low ozone concentrations and used in medicine as an alternative/adjuvant treatment for different diseases.
M. Costanzo   +6 more
doaj   +1 more source

Spandrels of the cell nucleus

open access: yesCurrent Opinion in Cell Biology
S.J. Gould and R. Lewontin in their famous "Spandrels paper" (1979) argued that many anatomical elements arise in evolution not due to their "current utility" but rather due to other "reasons for origin", such as other developmental processes, physical constraints and mechanical forces.
Irina Solovei, Leonid Mirny
openaire   +3 more sources

The sensitive period for the morphological effects of monocular deprivation in two nuclei of the tectofugal pathway of zebra finches [PDF]

open access: yes, 1988
Herrmann K, Bischof H-J. The sensitive period for the morphological effects of monocular deprivation in two nuclei of the tectofugal pathway of zebra finches. Brain Research.
Herrmann, Kathrin, Bischof, Hans-Joachim
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Novel Scaffold Based on Chitosan Hydrogels/Phthalated Cashew Gum for Supporting Human Dental Pulp Stem Cells

open access: yesPharmaceuticals, 2023
Hydrogels are structures that have value for application in the area of tissue engineering because they mimic the extracellular matrix. Naturally obtained polysaccharides, such as chitosan (CH) and cashew gum, are materials with the ability to form ...
Yulla Klinger de Carvalho Leite   +14 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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