Results 141 to 150 of about 827,170 (307)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Action Potential Timing Precision in Dorsal Cochlear Nucleus Pyramidal Cells

, 2007
Sarah E. Street, Paul B. Manis
openalex   +1 more source

Additional file 6 of Integrated transcriptome and proteome analyses identify novel regulatory network of nucleus pulposus cells in intervertebral disc degeneration

, 2021
Xu Chen, Shengchang Luo, Leixin Wei, Huiqiao Wu, Wei Gu, Wenchao Zhou, Baifeng Sun, Bo Hu, Hongyu Zhou, Yang Liu, Huajiang Chen, Xiaojian Ye, Wen Yuan   +12 more
openalex   +1 more source

An Integrative Segmentation Framework for Cell Nucleus of Fluorescence Microscopy. [PDF]

Genes (Basel), 2022
Pan W, Liu Z, Song W, Zhen X, Yuan K, Xu F, Lin GN.   +6 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Changes in the human nuclear chromatin induced by ultra wideband pulse irradiation

Open Life Sciences, 2009
Shckorbatov Yuriy, Pasiuga Vladimir, Kolchigin Nicolai, Batrakov Dmitry, Kazansky Oleg, Kalashnikov Vladimir   +5 more
doaj   +1 more source

Background and tandem‐pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus

, 2003
Jaehee Han, Carmen Gnatenco, Celia D. Sladek, Donghee Kim   +3 more
openalex   +1 more source

Dual supervised sampling networks for real-time segmentation of cervical cell nucleus. [PDF]

Comput Struct Biotechnol J, 2022
Luo D, Kang H, Long J, Zhang J, Chen L, Quan T, Liu X.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source