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BioEssays, 1988
AbstractThe origin of mitosis and the nuclear envelope were the pivotal processes in the evolutionary origin of the nucleus; they probably occurred in a wall‐less mutant bacterium that evolved a cytoskeleton and phagocytosis about 1500 million years ago.
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AbstractThe origin of mitosis and the nuclear envelope were the pivotal processes in the evolutionary origin of the nucleus; they probably occurred in a wall‐less mutant bacterium that evolved a cytoskeleton and phagocytosis about 1500 million years ago.
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Protein Synthesis in the Cell Nucleus
Nature, 1955THERE is considerable evidence that the cytoplasm of the cell contains structures capable of carrying out protein synthesis1, and it has been shown in one case2 that formation of protein may be little affected by removal of the nucleus. These findings seem to exclude the appealing hypothesis that the nucleus is the source of the cell's proteins.
David M. Prescott, Daniel Mazia
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Influenza A virus and the cell nucleus
Vaccine, 2006It is over 20 years since the publication of experiments that showed that influenza A virus RNA synthesis takes place in the cell nucleus and that here, the virus subverts the cellular transcription machinery to express and replicate its own single-strand RNA genome. In the years since, our understanding of the organisation of the nucleus has increased
Paul Digard, Maria João Amorim
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Protein Import into the Cell Nucleus
Annual Review of Cell Biology, 1986It has been known for some time that the uptake of proteins by the nucleus is extremely selective (Gurdon 1970; Bonner 1975b) and that mature nuclear proteins are able to accumulate in the nucleus (Gurdon 1970; Bonner 1975b; De Robertis et al 1978; Dabauvalle & Franke 1982).
Ronald A. Laskey, Colin Dingwall
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Cell Biology of the Plant Nucleus
Annual Review of Plant Biology, 2017The eukaryotic nucleus is enclosed by the nuclear envelope, which is perforated by the nuclear pores, the gateways of macromolecular exchange between the nucleoplasm and cytoplasm. The nucleoplasm is organized in a complex three-dimensional fashion that changes over time and in response to stimuli.
David E. Evans +3 more
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Role of glutathione in cell nucleus
Free Radical Research, 2010Cells with high proliferation rate have high glutathione levels. This typical feature of cancer cells is viewed usually as a defence mechanism against ionizing radiation or chemotherapy. Efforts have been made in order to decrease cellular glutathione levels in tumours as a necessary pre-treatment for cancer therapy.
Jose Viña +4 more
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Architecture of the Cell Nucleus
2010The nucleus is the largest of the cellular compartments, housing the chromosomes with the vast majority of the cellular genome, as well as multiple molecular machineries necessary for gene organisation and expression. During the past years contemporarily with the successful sequencing of the entire human genome, knowledge of nuclear architectures has ...
Jürgen Roth, Margit Pavelka
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Development of Virus in the Cell Nucleus
Nature, 1953THE nuclear polyhedral viruses of insects offer a unique opportunity for the study of virus behaviour in the cell. By knowing that the dominant focus of virus activity is in the cell nucleus, there is the advantage of being able to concentrate attention on a small and very definite site.
N. Xeros, Kenneth M. Smith
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Dynamic organization of the cell nucleus
Current Opinion in Genetics & Development, 2007The dynamic organization of the cell nucleus into subcompartments with distinct biological activities represents an important regulatory layer for cell function. Recent studies provide new insights into the principles, by which nuclear organelles form.
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The reactivation of the red cell nucleus
Journal of Cell Science, 1967ABSTRACT When the nucleus of a mature hen erythrocyte is introduced into the cytoplasm of a HeLa cell it resumes the synthesis of RNA and DNA. This reactivation of the red cell nucleus in the heterokaryon is associated with a marked increase in its volume. There is a direct relationship between the volume of the nucleus and the amount of
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