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Protein Synthesis in the Cell Nucleus
Nature, 1955THERE is considerable evidence that the cytoplasm of the cell contains structures capable of carrying out protein synthesis1, and it has been shown in one case2 that formation of protein may be little affected by removal of the nucleus. These findings seem to exclude the appealing hypothesis that the nucleus is the source of the cell's proteins.
D, MAZIA, D M, PRESCOTT
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Macromolecular Domains within the Cell Nucleus
Annual Review of Cell Biology, 1993DNA REPLICATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 TRANSCRIPTION AND PRE-mRNA PROCESSING .... . . ) ....... ,.... 279 Localization of Transcriptionally Active Nuclear Regions by [ HJ-Uridine Incorporation or In Situ Nick Translation . . . . . . . . . . . . . . . . 279 Pre-mRNA Splicing . . . . . . . . . . .
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Cell Biology of the Plant Nucleus
Annual Review of Plant Biology, 2017The eukaryotic nucleus is enclosed by the nuclear envelope, which is perforated by the nuclear pores, the gateways of macromolecular exchange between the nucleoplasm and cytoplasm. The nucleoplasm is organized in a complex three-dimensional fashion that changes over time and in response to stimuli.
Iris, Meier +2 more
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Role of glutathione in cell nucleus
Free Radical Research, 2010Cells with high proliferation rate have high glutathione levels. This typical feature of cancer cells is viewed usually as a defence mechanism against ionizing radiation or chemotherapy. Efforts have been made in order to decrease cellular glutathione levels in tumours as a necessary pre-treatment for cancer therapy.
Jelena, Markovic +4 more
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Functional architecture in the cell nucleus
Biochemical Journal, 2001The major functions of the cell nucleus, including transcription, pre-mRNA splicing and ribosome assembly, have been studied extensively by biochemical, genetic and molecular methods. An overwhelming amount of information about their molecular mechanisms is available. In stark contrast, very little is known about how these processes are integrated into
M, Dundr, T, Misteli
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Dynamic organization of the cell nucleus
Current Opinion in Genetics & Development, 2007The dynamic organization of the cell nucleus into subcompartments with distinct biological activities represents an important regulatory layer for cell function. Recent studies provide new insights into the principles, by which nuclear organelles form.
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Editorial overview: Cell nucleus
Current Opinion in Cell Biology, 2019Naoko, Imamoto, Daniel, Larson
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