Results 211 to 220 of about 23,513,766 (356)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Chronic asymptomatic orchitis in dogs alters Sertoli cell number and maturation status. [PDF]

Front Vet Sci
Rehder P, Packeiser EM, Körber H, Goericke-Pesch S.   +3 more
europepmc   +1 more source

Insulin-like Growth Factor Receptor 1 (IGF1R) Gene Copy Number Is Associated With Survival in Operable Non–Small-Cell Lung Cancer: A Comparison Between IGF1R Fluorescent In Situ Hybridization, Protein Expression, and mRNA Expression [PDF]

, 2010
Rafał Dziadziuszko, Daniel T. Merrick, Samir E. Witta, Adelita D. Mendoza, Barbara Szostakiewicz, Amelia Szymanowska, Witold Rzyman, Katarzyna Dziadziuszko, Jacek Jassem, Paul A. Bunn, Marileila Varella‐Garcia, Fred R. Hirsch   +11 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Issues on microbial soil remediation: a case of Cd detoxification by Bacillus strains for alleviating heavy metal stress in crop plants

Frontiers in Microbiology
Yini Shi, Xianyang Feng, Zhongke Sun, Boyuan Zhang, Chengwei Li, Chengwei Li   +5 more
doaj   +1 more source

The Coexistence of Bicellular and Tricellular Pollen Might Be the Third Type of Pollen Cell Number: Evidence from Annonaceae. [PDF]

Biology (Basel)
Gan Y, Zhang Q, Xiao C, Ping J.
europepmc   +1 more source

Somatic copy number alterations detected by ultra-deep targeted sequencing predict prognosis in oral cavity squamous cell carcinoma [PDF]

, 2015
Chien-Hua Peng, Chun‐Ta Liao, Ka-Pou Ng, An‐Shun Tai, Shih-Chi Peng, Jen-Pao Yeh, Shu‐Jen Chen, Kuo‐Chien Tsao, Tzu‐Chen Yen, Wen‐Ping Hsieh   +9 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Peripheral blood mononuclear cell number and paracrine function in responses to a 50-km trail race: An exploratory study. [PDF]

Physiol Rep
Landers-Ramos RQ, Kim K, Heilman J, Evans WS, Addison O, Ranadive SM, Prior SJ.   +6 more
europepmc   +1 more source

Immune Cell Number, Phenotype, and Function in the Elderly with Sepsis. [PDF]

Aging Dis, 2021
He W, Xiao K, Fang M, Xie L.
europepmc   +1 more source