Results 21 to 30 of about 123,277 (224)

Micropatterned substrates for studying astrocytes in culture

open access: yesFrontiers in Neuroscience, 2009
Recent studies of the physiological roles of astrocytes have ignited renewed interest in the functional significance of these glial cells in the central nervous system.
William Lee, Vladimir Parpura
doaj   +1 more source

A Parsimonious Model of the Rabbit Action Potential Elucidates the Minimal Physiological Requirements for Alternans and Spiral Wave Breakup. [PDF]

open access: yesPLoS Computational Biology, 2016
Elucidating the underlying mechanisms of fatal cardiac arrhythmias requires a tight integration of electrophysiological experiments, models, and theory.
Richard A Gray, Pras Pathmanathan
doaj   +1 more source

Exercise-Induced Skeletal Muscle Adaptations Alter the Activity of Adipose Progenitor Cells. [PDF]

open access: yesPLoS ONE, 2016
Exercise decreases adiposity and improves metabolic health; however, the physiological and molecular underpinnings of these phenomena remain unknown. Here, we investigate the effect of endurance training on adipose progenitor lineage commitment.
Daniel Zeve   +3 more
doaj   +1 more source

Hormone-switching islet cells: parallels to transmitter-switching neurons

open access: yesFrontiers in Cell and Developmental Biology
Although originating from different germ layers, pancreatic islet cells and neurons share extensive similarities, both physiological (e.g., voltage-dependent release of a bioactive molecule) and molecular (e.g., highly similar composition of ...
Yuval Dor, Nicholas C. Spitzer
doaj   +1 more source

Single cell sequencing in the study of hematopoietic system: application and perspects

open access: yesDi-san junyi daxue xuebao, 2021
Single cell sequencing (SCS) is a technique for precise analysis of cells at an individual level, which provides a new perspective on the identification of individual cell types, functions, states and interactions with other cells, and greatly deepens ...
WANG Junping, CHEN Naicheng
doaj   +1 more source

Cytoskeletal proteins and morphogenesis in planarians [PDF]

open access: yesInvertebrate Survival Journal, 2006
Regeneration processes employ a series of differentiative events related to various embryonic morphogenetic phenomena in which the cytoskeleton plays a fundamental role.
A Fagotti   +3 more
doaj   +1 more source

Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications

open access: yesMediators of Inflammation, 2015
The transforming growth factor beta (TGF-β) family forms a group of three isoforms, TGF-β1, TGF-β2, and TGF-β3, with their structure formed by interrelated dimeric polypeptide chains.
Łukasz A. Poniatowski   +3 more
doaj   +1 more source

Positron Emission Tomography (PET) radiotracers in oncology – utility of 18F-Fluoro-deoxy-glucose (FDG)-PET in the management of patients with non-small-cell lung cancer (NSCLC)

open access: yesJournal of Experimental & Clinical Cancer Research, 2008
PET (Positron Emission Tomography) is a nuclear medicine imaging method, frequently used in oncology during the last years. It is a non-invasive technique that provides quantitative in vivo assessment of physiological and biological phenomena.
Zullo Angelo   +8 more
doaj   +1 more source

An Agent-Based Interpretation of Leukocyte Chemotaxis in Cancer-on-Chip Experiments

open access: yesMathematics, 2022
The present paper was inspired by recent developments in laboratory experiments within the framework of cancer-on-chip technology, an immune-oncology microfluidic chip aiming at studying the fundamental mechanisms of immunocompetent behavior. We focus on
Gabriella Bretti, Andrea De Gaetano
doaj   +1 more source

Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics.
Mustafa Burak Acar   +10 more
doaj   +1 more source

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