Results 41 to 50 of about 124,652 (274)

Single cell sequencing in the study of hematopoietic system: application and perspects

Di-san junyi daxue xuebao, 2021
Single cell sequencing (SCS) is a technique for precise analysis of cells at an individual level, which provides a new perspective on the identification of individual cell types, functions, states and interactions with other cells, and greatly deepens ...
WANG Junping, CHEN Naicheng
doaj   +1 more source

Chemo-mechanical triggering of membrane potential at single cell level [PDF]

, 2022
openRapid changes in cell membrane potential are associated with important physiological phenomena such as the release of neurotransmitters in neurons, and contraction in cardiomyocytes.
PACCAGNAN, GIACOMO
core  

Hormone-switching islet cells: parallels to transmitter-switching neurons

Frontiers in Cell and Developmental Biology
Although originating from different germ layers, pancreatic islet cells and neurons share extensive similarities, both physiological (e.g., voltage-dependent release of a bioactive molecule) and molecular (e.g., highly similar composition of ...
Yuval Dor, Nicholas C. Spitzer
doaj   +1 more source

Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications

Mediators of Inflammation, 2015
The transforming growth factor beta (TGF-β) family forms a group of three isoforms, TGF-β1, TGF-β2, and TGF-β3, with their structure formed by interrelated dimeric polypeptide chains.
Łukasz A. Poniatowski, Piotr Wojdasiewicz, Robert Gasik, Dariusz Szukiewicz   +3 more
doaj   +1 more source

Cytoskeletal proteins and morphogenesis in planarians [PDF]

Invertebrate Survival Journal, 2006
Regeneration processes employ a series of differentiative events related to various embryonic morphogenetic phenomena in which the cytoskeleton plays a fundamental role.
A Fagotti, F Simoncelli, I Di Rosa, R Pascolini   +3 more
doaj   +1 more source

An Agent-Based Interpretation of Leukocyte Chemotaxis in Cancer-on-Chip Experiments

Mathematics, 2022
The present paper was inspired by recent developments in laboratory experiments within the framework of cancer-on-chip technology, an immune-oncology microfluidic chip aiming at studying the fundamental mechanisms of immunocompetent behavior. We focus on
Gabriella Bretti, Andrea De Gaetano
doaj   +1 more source

DNMTs are required for delayed genome instability caused by radiation [PDF]

, 2012
This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited ...
Anderson, Rhona, Iyer Pooja (7605638), Sandhu, J, Talbot, CJ, Jatinderpal Sandhu (2369116), Narayanan, D, Singh, Rajinder, Tufarelli, Cristina, Anderson, RM, Iyer, P, Deepan Narayanan (7605641), Sandhu, Jatinderpal, Tufarelli, C, Rajinder Singh (246689), Singh, R, George D. Jones (7605635), R. Anderson (3529871), Armstrong, CA, Christopher J. Talbot (7581152), Iyer, Pooja, Jones, GD, C Tufarelli (7605644), Narayanan, Deepan, Christine A. Armstrong (7605632), Armstrong, Christine A., Jones, George Tripp, Talbot, Christopher J.   +26 more
core   +1 more source

Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells

Frontiers in Bioengineering and Biotechnology, 2021
Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics.
Mustafa Burak Acar, Şerife Ayaz-Güner, Zeynep Gunaydin, Musa Karakukcu, Gianfranco Peluso, Giovanni Di Bernardo, Servet Özcan, Servet Özcan, Umberto Galderisi, Umberto Galderisi, Umberto Galderisi   +10 more
doaj   +1 more source

Positron Emission Tomography (PET) radiotracers in oncology – utility of 18F-Fluoro-deoxy-glucose (FDG)-PET in the management of patients with non-small-cell lung cancer (NSCLC)

Journal of Experimental & Clinical Cancer Research, 2008
PET (Positron Emission Tomography) is a nuclear medicine imaging method, frequently used in oncology during the last years. It is a non-invasive technique that provides quantitative in vivo assessment of physiological and biological phenomena.
Zullo Angelo, Tomao Federica, Spinelli Gian, Miele Evelina, De Marinis Filippo, Pasciuti Giulia, Rossi Luigi, Zoratto Federica, Tomao Silverio   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source