Dominant T-cell Receptor Delta Rearrangements in B-cell Precursor Acute Lymphoblastic Leukemia: Leukemic Markers or Physiological γδ T Repertoire? [PDF]
, 2023 Acute lymphoblastic leukemia (ALL) is an aggressive hematological malignancy characterized by clonal expansion of aberrant B- and T-cell precursor lymphoid cells.
Monika Brüggemann +23 more
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Next-generation in vitro blood–brain barrier models: benchmarking and improving model accuracy
Fluids and Barriers of the CNS, 2021 With the limitations associated with post-mortem tissue and animal models, In vitro BBB models enable precise control of independent variables and microenvironmental cues, and hence play an important role in studying the BBB.
Raleigh M. Linville, Peter C. Searson
doaj +1 more source
CD4+ T-Cell Activation Prompts Suppressive Function by Extracellular Vesicle-Associated MicroRNAs
, 2021 MicroRNAs (miRNAs), small non-coding molecules targeting messenger RNAs and inhibiting protein translation, modulate key biological processes, including cell growth and development, energy utilization, and homeostasis.
Prattichizzo F. +8 more
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CONSIDERATIONS REGARDING WATER RADIOACTIVITY AND ITS EFFECTS ON THE BODY [PDF]
Fiabilitate şi Durabilitate, 2019 The physiological action of radioactive waters can be manifested by complex effects that result in modifications or destruction of living cells. In the body, however, under the action of radiation, inverse phenomena of cell renewal can also occur, so ...
Daniela CÎRŢÎNĂ
doaj
Significance of Hydrogen Sulfide Production in the Pancreatic β-Cell
Journal of Pharmacological Sciences, 2011 .: Hydrogen sulfide (H2S) is an important signaling molecule in various mammalian cells and tissues. H2S is synthesized from l-cysteine and regulates several cellular and physiological phenomena (vasorelaxation, hormone secretion, and apoptosis) and ...
Shigeki Taniguchi, Ichiro Niki
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Growth-factor-induced, persistent fibroblast migration is mediated by mechanical insulation of cell front and back [PDF]
, 2014 Cell migration is a crucial process during development, the immune response and wound healing. As a consequence, aberrant cell migration can lead to tumor metastasis or autoimmune disorders.
Martin, Katrin
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Micropatterned substrates for studying astrocytes in culture
Frontiers in Neuroscience, 2009 Recent studies of the physiological roles of astrocytes have ignited renewed interest in the functional significance of these glial cells in the central nervous system.
William Lee, Vladimir Parpura
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A Parsimonious Model of the Rabbit Action Potential Elucidates the Minimal Physiological Requirements for Alternans and Spiral Wave Breakup. [PDF]
PLoS Computational Biology, 2016 Elucidating the underlying mechanisms of fatal cardiac arrhythmias requires a tight integration of electrophysiological experiments, models, and theory.
Richard A Gray, Pras Pathmanathan
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Numerical study of substrate assimilation by a microorganism exposed to fluctuating concentration [PDF]
, 2012 In most modelling works on bioreactors, the substrate assimilation is computed from the volume average concentration. The possible occurrence of a competition between the transport of substrate towards the cell and the assimilation at the cell level is ...
Martins Afonso, Marco +4 more
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Exercise-Induced Skeletal Muscle Adaptations Alter the Activity of Adipose Progenitor Cells. [PDF]
PLoS ONE, 2016 Exercise decreases adiposity and improves metabolic health; however, the physiological and molecular underpinnings of these phenomena remain unknown. Here, we investigate the effect of endurance training on adipose progenitor lineage commitment.
Daniel Zeve +3 more
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