Results 31 to 40 of about 12,054,912 (243)

The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells [PDF]

, 2007
We have addressed the role of the inducible costimulator (ICOS) in the development of T cell help for B cells and in the generation, survival and reactivation of memory CD4 T cells and B cells.
MacDonald, Andrew, Mahajan, Simmi, Fillatreau, Simon, Cervera, Ana, MacDonald, Andrew; id_orcid, Smith, Andrew, Gray, David, Ana Cervera, Perona-Wright, Georgia, Macleod, Megan, Andrew Smith, Stephen Meek, Megan MacLeod, Andrew MacDonald, Meek, Stephen, Simmi Mahajan, David Gray, Georgia Perona‐Wright, Simon Fillatreau   +18 more
core   +1 more source

Expansion Load and the Evolutionary Dynamics of a Species Range [PDF]

, 2015
Expanding populations incur a mutation burden, the socalled expansion load. Using a mixture of individual-based simulations and analytical modeling, we study the expansion load process in models where population growth depends on the population's ...
Excoffier, Laurent, Peischl, Stephan, Kirkpatrick, Mark, Peischl S, Kirkpatrick M, Excoffier L   +5 more
core   +2 more sources

Specific Bias Design in Cell Range Expansion for Picocell Network

Dianxin kexue, 2012
As an important part of the heterogeneous deployments,picocells are flexible to be deployed,easy to be planned and better for outdoor coverage.Due to the coexistence of macro and micro base stations,interference environment is complex,but also brought ...
Le Men, Tan Wang
doaj   +2 more sources

Historical and recent processes shaping the geographic range of a rocky intertidal gastropod: phylogeography, ecology, and habitat availability [PDF]

, 2014
Factors shaping the geographic range of a species can be identified when phylogeographic patterns are combined with data on contemporary and historical geographic distribution, range-wide abundance, habitat / food availability and through comparisons ...
Karine Posbic, Posbic, Karine, Posbic, K., Michael E. Hellberg, Hellberg, M.E., Hellberg, Michael E., Fenberg, P.B., Fenberg, Phillip B., Phillip B. Fenberg   +8 more
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Optimizing interleukin-2 concentration, seeding density and bead-to-cell ratio of T-cell expansion for adoptive immunotherapy

BMC Immunology, 2021
Background The successful ex vivo expansion of T-cells in great numbers is the cornerstone of adoptive cell therapy. We aimed to achieve the most optimal T-cell expansion condition by comparing the expansion of T-cells at various seeding densities, IL-2 ...
Sasan Ghaffari, Monireh Torabi-Rahvar, Sajjad Aghayan, Zahra Jabbarpour, Kobra Moradzadeh, Azadeh Omidkhoda, Naser Ahmadbeigi   +6 more
doaj   +1 more source

Dynamic CRE Bias Selection Algorithm Based on Heuristic Reinforcement Learning [PDF]

Jisuanji gongcheng, 2020
With the number of communication users increasing,the load of low-power base stations gets unbalanced,resulting in the gradually rising interference of cell edge users followed by reduced communication quality of the whole cell.To address the problem ...
GU Jing, DENG Yifei, ZHANG Xin
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Intelligent Dynamic Power Control with Cell Range Expansion for Small-Cells in 5G HetNets

Applied Sciences
In 5G heterogeneous networks (HetNets), small-cell base stations (SBSs) are deployed in the coverage of macro base stations (MBSs) to improve the system performance.
Ilhak Ban, Se-Jin Kim
doaj   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source