Results 51 to 60 of about 12,054,912 (243)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling the effect of habitat fragmentation on range expansion in a butterfly [PDF]

, 2009
There is an increasing need for conservation programmes to make quantitative predictions of biodiversity responses to changed environments. Such predictions will be particularly important to promote species recovery in fragmented landscapes, and to ...
Thomas, Chris D., C. D Thomas, Davies, Zoe G., Z. G Davies, R. J Wilson, Wilson, Robert J.   +5 more
core   +1 more source

In situ high-temperature X-ray diffraction of La0.6Sr0.4Co1 – xMoxO3 – δ (x = 0.0–0.10) oxides used as cathodes for solid oxide fuel cells [PDF]

Электрохимическая энергетика
The dependence of thermal expansion on the composition and atmosphere for molybdenumdoped lanthanum-strontium cobaltite La0.6Sr0.4Co1−xMoxO3−δ (х = 0–0.10) was studied by in situ hightemperature X-ray diffraction method (HTXRD ...
Gongola, Marko I., Vlasov, Stepan A., Popov, Mikhail P., Nemudry, Alexander P.   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes

, 2020
Deriving a large number of hiPSC-cardiomyocytes would be beneficial for large-scale tissue engineering and drug screening applications. Buikema et al.
Schuldt, Maike, Wu, Joy Y., van der Velden, Jolanda, Paik, David T, Tian, Lei, Wu, Joseph C., Buikema, Jan W., Sluijter, Joost P.G., Garcia, K Christopher, Fleischmann, Bernd K, Li, Guang, Wijnker, Paul, Wu, Joy Y, Dorsch, Larissa M., Doevendans, Pieter A., Puluca, Nazan, Paige, Sharon L., Rhee, Siyeon, Jovinge, Stefan, Maas, Renee G, Wu, Haodi, Goodyer, William R, Goodyer, William R., Venkamatran, Sneha, Paige, Sharon L, Paik, David T., Red-Horse, Kristy, Hesse, Michael, Wu, Sean M., Miao, Yi, Beck, Aimee, Garcia, K. Christopher, Dorsch, Larissa M, Buikema, Jan W, Geisen, Caroline, Serpooshan, Vahid, Doevendans, Pieter A, Chirikian, Orlando, Wu, Sean M, Swami, Srilatha, Fleischmann, Bernd K., Lee, Daniel, Galdos, Francisco X., van Mil, Alain, Beyersdorf, Benjamin, Hu, James, Wu, Joseph C, Maas, Renee G., Sluijter, Joost P G, Galdos, Francisco X, Lee, Soah, Arts Assistenten Cardiologie, Experimentele Afd. Cardiologie 2, Circulatory Health, Regenerative Medicine and Stem Cells, Onderzoek Cardiovasculair Reg. Med., Team Medisch   +56 more
core   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors [PDF]

, 2019
Objective For optimized expansion of human-induced pluripotent stem cells (hiPSCs) with regards to clinical applications, we investigated the influence of the inoculum density on the expansion procedure in 3D hollow-fibre bioreactors.
Miki, Toshio, Mandenius, Carl-Fredrik, Frank Schubert, Mandenius, Carl-Fredrik,, Hanci, Güngör, Schubert, Frank,, Freyer, Nora, Mike Böhme, Boehme, Mike,, Zeilinger, Katrin, Michael Sittinger, Sittinger, Michael,, Greuel, Selina, Miki, Toshio,, Boehme, Mike, Carl‐Fredrik Mandenius, Böhme, Mike, Nora Freyer, Mandenius, Carl‐Fredrik, Schubert, Frank, Zeilinger, Katrin,, Hanci, Guengoer, Güngör Hanci, Freyer, Nora,, Selina Greuel, Greuel, Selina,, Hanci, Guengoer,, Sittinger, Michael, Katrin Zeilinger, Toshio Miki   +29 more
core   +1 more source

Negative thermal expansion properties in tetragonal NbPO5 from the first principles studies

AIP Advances, 2017
By using the first-principles calculations based on density functional theory combined with quasi-harmonic approximation, we have studied the geometric structural, thermal properties, and the negative thermal expansion (NTE) properties of tetrahedral ...
Tao Li, Xiaonan Fu, Dahu Chang, Qiang Sun, Fei Wang   +4 more
doaj   +1 more source