Results 91 to 100 of about 5,589,399 (306)

Early Decrease in Respiration and Uncoupling Event Independent of Cytochrome c Release in PC12 Cells Undergoing Apoptosis [PDF]

open access: yes, 2012
Cytochrome c is a key molecule in mitochondria-mediated apoptosis. It also plays a pivotal role in cell respiration. The switch between these two functions occurs at the moment of its release from mitochondria.
Elisabetta Ferraro   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Comparison of different objective functions for parameterization of simple respiration models [PDF]

open access: yes, 2008
The eddy covariance measurements of carbon dioxide fluxes collected around the world offer a rich source for detailed data analysis. Simple, aggregated models are attractive tools for gap filling, budget calculation, and upscaling in space and time.
Richardson, A.   +3 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Influence of cyclophosphamide on respiration and membrane permeability of plant cells

open access: yesActa Societatis Botanicorum Poloniae, 2014
A specific influence of cyclophosphamide, an oncostatic drug of the group of alkylating agents, has been demonstrated on cellular respiration and the permeability of cell membranes.
Maria Podbielkowska   +2 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Zinc-Based Nanoparticles, but Not Silicon-Based Nanoparticles, Accumulate in Mitochondria and Promote Cell Death in Liver Cancer Cells

open access: yesInternational Journal of Nanomedicine
Joana C Pieretti,1,2 Thaissa L Horne,1 Natalia García-Villasante,1 Amedea B Seabra,2 Jordi Muntané1,3,4 1Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; 2Center for Natural ...
Pieretti JC   +4 more
doaj  

Carbon Isotope Fractionation in Plant Respiration

open access: yes, 2020
Carbon isotopes have long been used to dissect metabolic pathways. More recently, stable isotopes have become an important tool in modeling global fluxes in the biosphere, and notably CO2 isofluxes.
Badeck, Franz-W.   +2 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Correlation of mitochondrial respiration in platelets, peripheral blood mononuclear cells and muscle fibers

open access: yesHeliyon
There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less accessible tissues.
Emil Westerlund   +14 more
doaj   +1 more source

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