Results 141 to 150 of about 772,872 (263)

An activator of a two-component system controls cell separation and intrinsic drug resistance in <i><i>Mycobacterium tuberculosis</i></i>. [PDF]

Proc Natl Acad Sci U S A
McDonough LD, Li S, Munsamy-Govender V, Gwin CM, Rock JM, Rego EH.   +5 more
europepmc   +1 more source

Impact of buffer composition on biochemical, morphological and mechanical parameters: A tare before dielectrophoretic cell separation and isolation. [PDF]

Transl Oncol, 2023
Bonacci PG, Caruso G, Scandura G, Pandino C, Romano A, Russo GI, Pethig R, Camarda M, Musso N.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Validation of a New High-Throughput Cell Separation Method for Downstream Molecular Applications. [PDF]

Int J Mol Sci
Shillingford D, Radek A, Kupitz A, Thomas R, Connor C, Adams SP.   +5 more
europepmc   +1 more source

Design and Development of a Traveling Wave Ferro-Microfluidic Device and System Rig for Potential Magnetophoretic Cell Separation and Sorting in a Water-Based Ferrofluid. [PDF]

Micromachines (Basel), 2023
Hewlin RL, Edwards M, Schultz C.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Therapeatic evaluation and single cell analysis of adipose stromal vascular fraction isolation from a commercial cell separation system. [PDF]

Stem Cell Res Ther
Han S, Zhang Q, Lu F, Cai J.
europepmc   +1 more source

Fundamentals of integrated ferrohydrodynamic cell separation in circulating tumor cell isolation. [PDF]

Lab Chip, 2021
Liu Y, Zhao W, Cheng R, Harris BN, Murrow JR, Hodgson J, Egan M, Bankey A, Nikolinakos PG, Laver T, Meichner K, Mao L.   +11 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The DigH glycosyl hydrolase is conditionally required for daughter cell separation in <i>Escherichia coli</i>. [PDF]

J Bacteriol
Bryant JC, Robbs EJ, Kurilung A, Dinkel BA, Nookaew I, Jorgenson MA.   +5 more
europepmc   +1 more source