Results 291 to 300 of about 1,676,735 (349)

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock, Jihyun Park, Dae‐Gyu Jang, Bangyao Zhao, Samuel J. Teener, Ian F. Webber‐Davis, Lili Zhao, Eva L. Feldman, Stephen A. Goutman   +8 more
wiley   +1 more source

High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li, Binbin Xue, Jia Li, Dewei Xie, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Xu Zhang, Junhui Xia, Jie Lin   +10 more
wiley   +1 more source

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Dielectrophoretic separation of cells: Continuous separation

Biotechnology and Bioengineering, 1995
AbstractDielectrophoresis is the movement of particles in non‐uniform alternating and direct current (AC, DC) electric fields. When nonuniform electric fields are created between microelectrodes, cells will redistribute themselves around the electrodes, the force holding the cells in place dependig on the local electric field and on the electrical ...
Gerard H. Markx, Ronald Pethig
openaire   +3 more sources

A separability parameter for dielectrophoretic cell separation

ELECTROPHORESIS, 2013
In this study, a separability parameter is introduced to determine the selection of optimum operating parameters for DEP separation of a cell pair. The separability parameter is defined as a function of cells’ Clausius–Mossotti (CM) factors. T‐cell leukemia Jurkat and mouse melanoma B16 cells are tested to validate the separability parameter.
Ali Beskok, Ahmet C. Sabuncu, Ahmet C. Sabuncu   +2 more
openaire   +3 more sources

Biophysics of cell separations

Quarterly Reviews of Biophysics, 1975
To the Chemist, it has long been second nature to work with separate, purified substances. Biochemists and molecular biologists have now largely achieved the same working position, with their powerful separation techniques of ultracentrifugation, electrophoresis, chromatography and the like.
D. W. Ross, Howard C. Mel
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Cell separation: a review

Pathology, 1984
This review summarizes currently available techniques for cell separation. Techniques that exploit differences in physical properties of cells are widely used but have a number of limitations. Those that are based on differences in surface properties may more readily permit reproducible separation of a functionally homogeneous population of cells ...
Rakesh K. Kumar, A. W. J. Lykke
openaire   +3 more sources

Microfluidics for cell separation

Medical & Biological Engineering & Computing, 2010
The need for efficient cell separation, an essential preparatory step in many biological and medical assays, has led to the recent development of numerous microscale separation techniques. This review describes the current state-of-the-art in microfluidics-based cell separation techniques.
Han Wei Hou, Han Wei Hou, Jongyoon Han, Jongyoon Han, Ali Asgar S. Bhagat, Swee Jin Tan, Hansen Bow, Chwee Teck Lim, Chwee Teck Lim   +8 more
openaire   +3 more sources

Cellulase and cell separation

Giornale botanico italiano, 1995
Abstract The involvement of cellulase (endo-b-l,4-glucanase, EC 3.2.1.4) in a number of different cell separation events which occur in higher plants has been well established. Besides their significance for the plant growth and differentiation, these events can be economically important since they also comprise softening of fleshy fruits and ...
CASADORO, GIORGIO, FERRARESE L., TRAINOTTI, LIVIO, MORETTO P., RASCIO, NICOLETTA   +4 more
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Synaptosomes and cell separation

Neuroscience, 1976
Publisher Summary When fractionating a complex tissue like brain, experiments should begin by separating it into its constituent cell classes. Any subcellular fraction prepared from brain is intrinsically heterogeneous as it is derived from several cell types.
openaire   +3 more sources