Results 61 to 70 of about 827,991 (338)
Micromachines, 2020 A microfluidic device is presented for the continuous separation of red blood cells (RBCs) and white blood cells (WBCs) in a label-free manner based on negative dielectrophoresis (n-DEP). An alteration of the electric field, generated by pairs of slanted
Tomoyuki Yasukawa +4 more
doaj +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Clustering and ordering in cell assemblies with generic asymmetric aligning interactions [PDF]
arXiv, 2020 Collective cell migration plays an essential role in various biological processes, such as development or cancer proliferation. While cell-cell interactions are clearly key determinants of collective cell migration -- in addition to individual cells self-propulsion -- the physical mechanisms that control the emergence of cell clustering and collective ...
arxiv
Pattern Formation of Glioma Cells: Effects of Adhesion [PDF]
EPL (Europhysics Letters) 88, 28006 (2009), 2008 We investigate clustering of malignant glioma cells. \emph{In vitro} experiments in collagen gels identified a cell line that formed clusters in a region of low cell density, whereas a very similar cell line (which lacks an important mutation) did not cluster significantly. We hypothesize that the mutation affects the strength of cell-cell adhesion. We
arxiv +1 more source
, 2021 Many processors are available for separating particles and/or cells, but few can match the capacity of flow cytometry – in particular the sorting component. Several aspects unique to cell sorting give it such power. First, particles can be separated based on size, complexity, fluorescence, or any combination of these parameters.
openaire +4 more sources
Current Directions in Biomedical Engineering, 2020 Within the human blood immune cells assume specific functions to modulate and control the human immune response. Consequently, they are used for the diagnosis and treatment of autoimmune and hematologic diseases.
Behrens Stephan +2 more
doaj +1 more source
Numerical Simulation of a Lab-on-Chip for Dielectrophoretic Separation of Circulating Tumor Cells
Micromachines, 2023 Circulating tumor cells (CTCs) are cancer cells detached from tumors that enter the bloodstream with the rest of the blood cells before settling on remote organs and growing. CTCs play a major role as a target for cancer diagnosis.
Abdallah M. Alkhaiyat, Mohamed Badran
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Comparison of Chip Inlet Geometry in Microfluidic Devices for Cell Studies
Molecules, 2016 Micro-fabricated devices integrated with fluidic components provide an in vitro platform for cell studies best mimicking the in vivo micro-environment. These devices are capable of creating precise and controllable surroundings of pH value, temperature ...
Yung-Shin Sun
doaj +1 more source
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source