Results 61 to 70 of about 13,183,605 (418)

Label-free ferrohydrodynamic cell separation of circulating tumor cells.

open access: yesLab on a Chip, 2017
Circulating tumor cells (CTCs) have significant implications in both basic cancer research and clinical applications. To address the limited availability of viable CTCs for fundamental and clinical investigations, effective separation of extremely rare ...
Wujun Zhao   +10 more
semanticscholar   +1 more source

High-Sensitivity in Dielectrophoresis Separations

open access: yesMicromachines, 2020
The applications of dielectrophoretic (DEP) techniques for the manipulation of cells in a label-free fashion within microfluidic systems continue to grow. However, a limited number of methods exist for making highly sensitive separations that can isolate
Benjamin G. Hawkins   +2 more
doaj   +1 more source

Continuous Magnetophoretic Separation of Blood Cells from Plasma at the Microscale [PDF]

open access: yes, 2007
We present a method for the direct and continuous separation of red and white blood cells from plasma at the microscale. The method is implemented in a microfluidic system with magnetic functionality. The fluidic structure within the microsystem consists of an inlet and a single microfluidic channel with multiple outlets.
arxiv   +1 more source

Fifty years of dielectrophoretic cell separation technology.

open access: yesBiomicrofluidics, 2016
In 1966, Pohl and Hawk [Science 152, 647-649 (1966)] published the first demonstration of dielectrophoresis of living and dead yeast cells; their paper described how the different ways in which the cells responded to an applied nonuniform electric field ...
M. Hughes
semanticscholar   +1 more source

High Throughput Separation of Cells Achieved Through the Particle Characteristic Dielectrophoretic Response and Further Focusing [PDF]

open access: yesarXiv, 2020
Previous devices to separate cells by the characteristic force they experience due to dielectrophoresis, which depends on the size and electric properties of the particle, were limited by the flow rates and particle concentrations separation could be achieved at.
arxiv  

Rapid cell separation with minimal manipulation for autologous cell therapies

open access: yesScientific Reports, 2017
The ability to isolate specific, viable cell populations from mixed ensembles with minimal manipulation and within intra-operative time would provide significant advantages for autologous, cell-based therapies in regenerative medicine.
A. J. Smith   +8 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Rapid, label‐free enrichment of lymphocytes in a closed system using a flow‐through microfluidic device

open access: yesBioengineering & Translational Medicine
The majority of adoptive cellular therapies are produced from peripheral mononuclear cells obtained via leukapheresis and further enriched for the cells of interest (e.g., T cells).
Anton Mukhamedshin   +7 more
doaj   +1 more source

Cell cycle-specific phase separation regulated by protein charge blockiness

open access: yesNature Cell Biology, 2022
Dynamic morphological changes of intracellular organelles are often regulated by protein phosphorylation or dephosphorylation1–6. Phosphorylation modulates stereospecific interactions among structured proteins, but how it controls molecular interactions ...
Hiroya Yamazaki   +4 more
semanticscholar   +1 more source

Performance Metrics for the Objective Assessment of Capacitive Deionization Systems [PDF]

open access: yes, 2018
In the growing field of capacitive deionization (CDI), a number of performance metrics have emerged to describe the desalination process. Unfortunately, the separation conditions under which these metrics are measured are often not specified, resulting ...
Biesheuvel, P. M.   +7 more
core   +2 more sources

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