Results 171 to 180 of about 14,296,855 (364)
Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation [PDF]
, 2004 Ping Ling +6 more
openalex +1 more source
Modulation of macrophage phenotype by cell shape
Proceedings of the National Academy of Sciences of the United States of America, 2013 Frances Y. McWhorter +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Nucleoid Morphology in E. Coli is Cell Shape Dependent [PDF]
, 2012 Jay K. Fisher
openalex +1 more source
Actin, a Central Player in Cell Shape and Movement
Science, 2009 T. Pollard, J. Cooper
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity
, 2013 Takashi Hato +2 more
openalex +2 more sources
Pervasive Correlated Evolution in Gene Expression Shapes Cell and Tissue Type Transcriptomes [PDF]
, 2018 Cong Liang +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source