Results 161 to 170 of about 2,203,683 (304)

Spectrin coordinates cell shape and signaling essential for epidermal differentiation. [PDF]

J Cell Biol
Soffer A, Bhosale A, Ghodrat R, Peskoller M, Matsui T, Niessen CM, Luxenburg C, Rübsam M.   +7 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Independent roles of Arp2/3 complex and RIC4 protein in the control of epidermal cell shape. [PDF]

Planta
García-González J, Havelková L, Bellinvia E, Corrales I, Pejchar P, Potocký M, Schwarzerová K.   +6 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A histidine pseudokinase modulates polar growth and cell shape in Streptomyces venezuelae. [PDF]

Commun Biol
Singh Mavi P, Flärdh K.
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Alanine-scanning mutagenesis library of MreB reveals distinct roles for regulating cell shape and viability. [PDF]

PLoS Genet
Maharjan S, Sloan R, Lusk J, Bevienguevarr R, Surber J, Morgenstein RM.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Non-linear stress-softening of peptidoglycan mediates bacterial cell shape homeostasis. [PDF]

Curr Biol
Bardetti P, Barber F, Fitzmaurice D, Rojas ER.   +3 more
europepmc   +1 more source

NUCLEAR SHAPE IN MUSCLE CELLS [PDF]

The Journal of Cell Biology, 1969
W W, Franke, W, Schinko
openaire   +2 more sources