Results 181 to 190 of about 14,296,855 (364)

Spectrin coordinates cell shape and signaling essential for epidermal differentiation. [PDF]

J Cell Biol
Soffer A, Bhosale A, Ghodrat R, Peskoller M, Matsui T, Niessen CM, Luxenburg C, Rübsam M.   +7 more
europepmc   +1 more source

The PHR Family: The Role of Extracellular Transglycosylases in Shaping Candida albicans Cells [PDF]

, 2017
Laura Popolo, Genny Degani, Carlo Camilloni, William A. Fonzi   +3 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cell shape and maturation impacts α-actinin-2 tension in iPSC-derived cardiomyocytes. [PDF]

APL Bioeng
Dutta PK, Toth JM, Sundaram S, Chen X, Chopra A, Ewoldt JK, Cloonan P, Gao X, LaCroix AS, Hoffman BD, Shenoy VB, Seidman CE, Seidman JG, Chen CS, Eyckmans J.   +14 more
europepmc   +1 more source

Staying in Shape: the Impact of Cell Shape on Bacterial Survival in Diverse Environments

Microbiology and Molecular Reviews, 2016
Desirée C. Yang, Kris M Blair, N. Salama   +2 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Diagnosis Support of Sickle Cell Anemia by Classifying Red Blood Cell Shape in Peripheral Blood Images

Wilkie Delgado-Font, Miriela Escobedo-Nicot, Manuel González-Hidalgo, Silena Herold-Garcia, Antoni Jaume-i-Capó, Arnau Mir   +5 more
openalex   +1 more source

The cell-shape protein MreC interacts with extracytoplasmic proteins including cell wall assembly complexes in Caulobacter crescentus

, 2005
Arun V. Divakaruni, Rachel R. Ogorzalek Loo, Yongming Xie, Joseph A. Loo, James W. Gober   +4 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape. [PDF]

Commun Biol
da Silva LE, Paim LMG, Lyalina T, Menezes APJ, da Cunha JPC, Bechstedt S, Cella N.   +6 more
europepmc   +1 more source