Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex
Emerging Infectious Diseases, 1997 Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
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ANTIGENIC STRUCTURE OF CELL SURFACES [PDF]
The Journal of Experimental Medicine, 1969 The representation of mouse alloantigens belonging to three systems, H-2, θ and TL, on the surface of cells from thymus, spleen, lymph nodes, and peritoneal cavity, was studied by electron microscopy with ferritin-labeled antibody. As expected from earlier serological data, TL was confined to thymocytes, θ was found on thymocytes and lymphocytes, and H-
Tadao Aoki +4 more
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Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]
, 2017 Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L +6 more
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Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity. [PDF]
PLoS ONE, 2014 Cell surface proteins have a wide range of biological functions, and are often used as lineage-specific markers. Antibodies that recognize cell surface antigens are widely used as research tools, diagnostic markers, and even therapeutic agents.
Craig A Gedye +26 more
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Amino-functionalized poly(l-lactide) lamellar single crystals as a valuable substrate for delivery of HPV16-E7 tumor antigen in vaccine development [PDF]
, 2015 Background: Poly(L-lactide) (PLLA) is a biodegradable polymer currently used in many biomedical applications, including the production of resorbable surgical devices, porous scaffolds for tissue engineering, nanoparticles and microparticles for the ...
Accardi, Luisa +8 more
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Viral Delivery of CAR Targets to Solid Tumors Enables Effective Cell Therapy
Molecular Therapy: Oncolytics, 2020 Chimeric antigen receptor (CAR) T cell therapy has had limited efficacy for solid tumors, largely due to a lack of selectively and highly expressed surface antigens.
Amin Aalipour +8 more
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Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. [PDF]
PLoS ONE, 2013 Surface molecule profiles undergo dynamic changes in physiology and pathology, serve as markers of cellular state and phenotype and can be exploited for cell selection strategies and diagnostics.
Gizem Turaç +7 more
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Improving cellular cancer vaccines [PDF]
, 2010 Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
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Journal of Experimental Medicine, 1977 As background for a serological definition of the unique antigens of chemically induced sarcomas, we have typed a series of fibroblast and sarcoma cell lines of BALB/c and C57BL/6 origin by cytoxicity and absorption tests for murine leukemia virus (MuLV)-
A. Deleo +4 more
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ALPPL2 Is a Highly Specific and Targetable Tumor Cell Surface Antigen
Cancer Research, 2020 These findings identify ALPP2 as a true tumor-specific cell surface antigen whose tissue specificity enables the development of novel therapies. Identification of tumor-specific cell surface antigens has proven challenging, as the vast majority of tumor ...
Yang Su +5 more
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