Results 41 to 50 of about 162,421 (123)

Hazards of lunar surface exploration: determining the immunogenicity/allergenicity of lunar dust

Frontiers in Immunology
Although infrequent, there have been Apollo program reports of lunar dust exposure leading to notable upper respiratory symptoms in select crewmembers.
Audrie A. Colorado, Cody L. Gutierrez, Mayra Nelman-Gonzalez, Gailen D. Marshall, J. Torin Mccoy, Brian E. Crucian   +5 more
doaj   +1 more source

Synthesis, single crystal structure, and Hirshfeld surface of (E)-N'-(2-hydroxybenzylidene)-2-((3- (trifluoromethyl)phenyl)amino)benzohydrazide

Macedonian Journal of Chemistry and Chemical Engineering
A hydrazide-hydrazone derivative, (E)-N'-(2-hydroxybenzylidene)-2-((3-(trifluoromethyl)phenyl) amino)benzohydrazide, was synthesized and characterized using various spectroscopic techniques such as FTIR, 1H-NMR and 13C-NMR spectroscopy, and X-ray ...
Hanifi Özşanli, Sude Saral Çakmak, Ufuk Çoruh, Sevgi Karakuş, Ezequiel M Vazquez-Lopez   +4 more
doaj   +1 more source

Structure and function of the open canalicular system – the platelet’s specialized internal membrane network

Platelets, 2018
The open canalicular system (OCS) is an internal membrane structure found in platelets. First identified 50 years ago, the OCS comprises a tunneling network of surface-connected channels that appear to play an important role in platelet function.
Maria V. Selvadurai, Justin R. Hamilton
doaj   +1 more source

Green Synthesis of Silver Nanoparticles with Bioreductant from Lime Juice Powder (Citrus aurantifolia): Effect of Concentration and pH

Indonesian Journal of Chemistry
Significant development in antibacterial agents derived from metal nanoparticles is currently underway. One commonly employed type is silver nanoparticles (AgNPs), which display potential antibacterial activity at lower concentrations compared to other ...
Septian Dwi Mulyana, Retno Sari, Agus Syamsur Rijal   +2 more
doaj   +1 more source

Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET.

PLoS ONE, 2012
The c-MET receptor has a function in many human cancers and is a proven therapeutic target. Generating antagonistic or therapeutic monoclonal antibodies (mAbs) targeting c-MET has been difficult because bivalent, intact anti-Met antibodies frequently ...
Sameer A Greenall, Ermanno Gherardi, Zhanqi Liu, Jacqueline F Donoghue, Angela A Vitali, Qian Li, Roger Murphy, Luisa Iamele, Andrew M Scott, Terrance G Johns   +9 more
doaj   +1 more source

Optimization algorithms for functional deimmunization of therapeutic proteins

BMC Bioinformatics, 2010
Background To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response.
Griswold Karl E, Zheng Wei, Parker Andrew S, Bailey-Kellogg Chris   +3 more
doaj   +1 more source

Toxicity of nuclear-localized GFP in reporter mice

Scientific Reports
Various techniques using fluorescent reporter probes have been developed, such as GFP transgenic mouse lines that are used to detect spatial–temporal expression levels of genes. Although GFP expression is largely considered non-toxic, recent reports have
Sudhir Verma, Isabel Y. Moreno, Tarsis F. Gesteira, Vivien J. Coulson-Thomas   +3 more
doaj   +1 more source

In vitro chronic effects on hERG channel caused by the marine biotoxin Yessotoxin.

Frontiers in Marine Science, 2014
INTRODUCTION Marine algal blooms caused by the overgrowth of marine phytoplankton have increased in frequency and severity in the last years; supposing a worldwide public health problem.
Sara Fernández Ferreiro
doaj   +1 more source

Postbiotics derived from recombinant lactic acid bacteria exhibit high IL6-binding capacity and suppress IL6-induced STAT3 signaling

Frontiers in Microbiology
IntroductionWith growing evidence of clinical efficacy of probiotics in various diseases, safety concerns have arisen regarding the therapeutic use of live probiotic bacteria, especially in critically ill, immunocompromised, and pediatric populations ...
Abida Zahirović, Špela Zupančič, Andraž Verdir, Sebastjan Nemec, Slavko Kralj, Slavko Kralj, Luka Snoj, Aleš Berlec, Aleš Berlec   +8 more
doaj   +1 more source

Tiny-Machine-Learning-Based Supply Canal Surface Condition Monitoring

Sensors
The South-to-North Water Diversion Project in China is an extensive inter-basin water transfer project, for which ensuring the safe operation and maintenance of infrastructure poses a fundamental challenge.
Chengjie Huang, Xinjuan Sun, Yuxuan Zhang   +2 more
doaj   +1 more source