Results 21 to 30 of about 161,349 (222)

SARS-CoV-2: preliminary study of infected human nasopharyngeal tissue by high resolution microscopy

Virology Journal, 2021
Background The novel coronavirus SARS-CoV-2 is the etiological agent of COVID-19. This virus has become one of the most dangerous in recent times with a very high rate of transmission.
Brian Mondeja, Odalys Valdes, Sonia Resik, Ananayla Vizcaino, Emilio Acosta, Adelmo Montalván, Amira Paez, Mayra Mune, Roberto Rodríguez, Juan Valdés, Guelsys Gonzalez, Daisy Sanchez, Viviana Falcón, Yorexis González, Vivian Kourí, The IPK Virology Research Group, Angelina Díaz, María Guzmán   +17 more
doaj   +1 more source

A Beautiful Bind: Phage Display and the Search for Cell-Selective Peptides

Viruses
Phage display has advanced the discovery of peptides that selectively bind to a wide variety of cell surface molecules, offering new modalities to modulate disease-related protein–protein interactions (PPIs).
Babak Bakhshinejad, Saeedeh Ghiasvand
doaj   +1 more source

A Comparative In Vitro and In Vivo Study of Osteogenicity by Using Two Biomaterials and Two Human Mesenchymal Stem Cell Subtypes

Frontiers in Cell and Developmental Biology, 2022
Background: Bone repair induced by stem cells and biomaterials may represent an alternative to autologous bone grafting. Mesenchymal stromal/stem cells (MSCs), easily accessible in every human, are prototypical cells that can be tested, alone or with a ...
L. Fievet, N. Serratrice, N. Serratrice, B. Brulin, L. Giraudo, J. Véran, N. Degardin, F. Sabatier, F. Féron, F. Féron, P. Layrolle   +10 more
doaj   +1 more source

Isolation and characterization of anti c-met single chain fragment variable (scFv) antibodies

Journal of Immunotoxicology, 2017
The receptor tyrosine kinase (RTK) Met is the cell surface receptor for hepatocyte growth factor (HGF) involved in invasive growth programs during embryogenesis and tumorgenesis.
Elmira Safaie Qamsari, Zahra Sharifzadeh, Salman Bagheri, Farhad Riazi-Rad, Vahid Younesi, Mohsen Abolhassani, Sepideh Safaei Ghaderi, Behzad Baradaran, Mohammad Hossein Somi, Mehdi Yousefi   +9 more
doaj   +1 more source

Influence of Substrates on the Surface Characteristics and Membrane Proteome of Fibrobacter succinogenes S85.

PLoS ONE, 2015
Although Fibrobacter succinogenes S85 is one of the most proficient cellulose degrading bacteria among all mesophilic organisms in the rumen of herbivores, the molecular mechanism behind cellulose degradation by this bacterium is not fully elucidated ...
Mahendra P Raut, Esther Karunakaran, Joy Mukherjee, Catherine A Biggs, Phillip C Wright   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

PRE-CLINICAL DEVELOPMENT OF HUMAN MONOCLONAL ANTIBODIES TARGETING NOVEL, CELL WALL PROTEINS IN DRUG RESISTANT FUNGAL PATHOGENS

International Journal of Infectious Diseases, 2023
Intro: As the world begins to “run out” of anti-fungal drug options, the development of next generation alternatives remains dogged by the need to kill a eukaryotic pathogen within a eukaryotic host.
S. Palliyil, C. Munro, A. Porter
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Novel Trypanosoma cruzi Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth. [PDF]

PLoS ONE, 2015
The flagellar pocket constitutes an active and strategic site in the body of trypanosomatids (i.e. parasitic protozoa that cause important human and/or livestock diseases), which participates in several important processes such as cell polarity ...
Ignacio M Durante, María de Los Milagros Cámara, Carlos A Buscaglia   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source