Results 201 to 210 of about 14,964,075 (408)

Cell turnover in mammalian tissues: use of cell depletion measurements to calculate x-ray reproductive survival curves in vivo. [PDF]

, 1965
Theodore T. Puck
openalex   +1 more source

TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.

Cell Stem Cell, 2019
Masayuki Yamashita, E. Passegué
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

HSP27 and cell survival in neurones

International Journal of Hyperthermia, 2005
Although the majority of studies on the protective effect of individual hsps have concentrated on the major inducible heat shock protein Hsp70, a variety of evidence suggests that the small heat shock protein Hsp27 may have a more potent protective effect in the nervous system.
openaire   +2 more sources

Metabolic pathways promoting cancer cell survival and growth

Nature Cell Biology, 2015
Lindsey K. Boroughs, R. Deberardinis
semanticscholar   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

xCG: Explainable Cell Graphs for Survival Prediction in Non-Small Cell Lung Cancer [PDF]

arXiv
Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on recent advances in the spatial modeling of the tumor microenvironment using graph neural networks, we present an ...
arxiv  

Survival of HeLa Cells from 10 Nanosecond Pulses of Electrons [PDF]

, 1970
A.H.W. Nias, A. J. Swallow, J. P. Keene, Brian Hodgson   +3 more
openalex   +1 more source

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

EMBO Journal, 2004
F. Yeung, Jamie E. Hoberg, Catherine S. Ramsey, Michael D Keller, David R. Jones, Roy A. Frye, M. Mayo   +6 more
semanticscholar   +1 more source