Results 231 to 240 of about 3,396,679 (311)

Apoptotic cells promote circulating tumor cell survival and metastasis. [PDF]

Commun Biol
Hagan CE, Sheehan VM, Rezanka CM, Li MA, Martínez-Escardó L, Campbell KJ, Snyder AG, Headley M, Oberst A.   +8 more
europepmc   +1 more source

CNS Remission Predicts Survival After Autologous Hematopoietic Stem Cell Transplantation (AHCT) For Non-Hodgkin Lymphoma (NHL) With Pre-Existing CNS Involvement: A CIBMTR Analysis

, 2010
Richard T. Maziarz, ZiXuan Wang, M.-J. Zhang, Ginna G. Laport, Hillard M. Lazarus, Silvia Montoto, Parameswaran Hari   +6 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

S100A9 enhances tumor immune suppression and cancer cell survival in small cell lung cancer. [PDF]

Cell Death Dis
Charan M, Mishra S, Shilo K, Zhang X, Verma AK, Ghanta P, Webb A, Ganju RK.   +7 more
europepmc   +1 more source

The effect of RES blockade on red blood cell survival.

, 1981
Tatsumi Uchida, Shin Matsuda, Tetsugoro TANAKA, Tadashi Sato, Tokuo Yui, R Kokubun, Masashi Kumano, S Kariyone   +7 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival. [PDF]

Nat Commun
Shibue K, Kahraman S, Castillo-Quan JI, De Jesus DF, Hu J, Morita H, Blackwell TK, Yi P, Kulkarni RN.   +8 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Compression-induced NF-κB activation sustains tumor cell survival in confinement by detoxifying aldehydes and promotes metastasis. [PDF]

Nat Commun
Liu B, Liu M, Zhang Y, Zhu Y, Zhou D, Gao H, Yang F, Gao D, Zhao Y, Tao B, Yao F, Yang W.   +11 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source