Results 251 to 260 of about 2,251,671 (317)

Induction of TFEB promotes Kupffer cell survival and reduces lipid accumulation in MASLD. [PDF]

Hepatol Commun
Chan MM, Daemen S, Beatty W, Byrnes K, Cho K, Ferguson D, Feldstein N, Park C, Guo Z, Park AC, Fu CF, Florczak KL, He L, Yang BQ, Javaheri A, Patti GJ, Finck BN, Razani B, Schilling JD.   +18 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors. [PDF]

Nat Commun
Shanmugam V, Tokcan N, Chafamo D, Sullivan S, Borji M, Martin H, Newton G, Nadaf N, Hanbury S, Barrera I, Cable D, Weir J, Ashenberg O, Pinkus G, Rodig S, Uhler C, Macosko E, Shipp M, Louissaint A, Chen F, Golub TR.   +20 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Critical Role of RPS4X in Modulating SCF Complex Formation and Cell Survival. [PDF]

Biomolecules
Ryu S, Kim MJ, Bando S, Tanaka Y, Mukai R, Ishihara Y, Tominaga T, Ohshima T.   +7 more
europepmc   +1 more source

SIRT6 Is a Key Regulator of Pancreatic β-Cell Survival and Function During Aging. [PDF]

Diabetes
Park J, Lokuge SD, Huang M, Wang S, Liu S, Liang J, Katturajan R, Marakovits C, Yang Z, Wan J, Dong XC.   +10 more
europepmc   +1 more source

HIF1A-mediated pathways promote euploid cell survival in chromosomally mosaic embryos. [PDF]

Elife
Sanchez-Vasquez E, Bronner ME, Zernicka-Goetz M.   +2 more
europepmc   +1 more source

Beyond Iron Solubility: Particle Size as a Determinant of Cell Survival and Iron-Induced COX-2 Expression in Human Intestinal Cells. [PDF]

Biomolecules
Tarczykowska A, Mohammadi AS, Scheers N.
europepmc   +1 more source

Hijacking the unfolded protein response (UPR) pathway: Balancing viral infection and host cell survival. [PDF]

J Biol Chem
Chen H, Liu D, Hua J, Wu M, Hua Y, Feng C, He Z, Moffett P, Zhang K.   +8 more
europepmc   +1 more source

Apoptotic cells promote circulating tumor cell survival and metastasis. [PDF]

Commun Biol
Hagan CE, Sheehan VM, Rezanka CM, Li MA, Martínez-Escardó L, Campbell KJ, Snyder AG, Headley M, Oberst A.   +8 more
europepmc   +1 more source