Results 261 to 270 of about 8,088,933 (310)
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Plasma cell differentiation and survival
Current Opinion in Immunology, 2008Humoral immunity depends on the regulated production and maintenance of antibody secreting cells during the course of an immune response. Recent insights into the transcriptional regulation of the initiation of plasma cell differentiation have clarified aspects of this process, particularly with respect to the choice between the memory B cell and ...
David, Tarlinton +3 more
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The British Journal of Radiology, 1980
Lokajiceek et al. (1979) have recently proposed an equation relating cell survival to TDF. Since TDF is additive, their equation (3) is The fraction of cells surviving after a course of irradiation is taken as or However, their conclusion that where α is a constant, is only true for the special case where the proportion of cell recovery between ...
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Lokajiceek et al. (1979) have recently proposed an equation relating cell survival to TDF. Since TDF is additive, their equation (3) is The fraction of cells surviving after a course of irradiation is taken as or However, their conclusion that where α is a constant, is only true for the special case where the proportion of cell recovery between ...
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Involvement of integrins in cell survival
Cancer and Metastasis Reviews, 1995Apoptosis is a regulated process of cell death by which cells actively participate in their own destruction. In multicellular organisms, the balance between cell proliferation and apoptosis provides homeostatic control, and a regulatory failure of either event can contribute to oncogenesis.
R C, Bates, L F, Lincz, G F, Burns
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Red cell survival in galactosemia
The Journal of Pediatrics, 1966Erythrocyte survival in a 4 1/2-year-old galactosemic patient was studied. In vitroautohemolysis of the patient's red cells was within normal limits in both the absence and presence of galactose. The half-lives of Cr 51 -tagged cells in the patient's circulation while he was on a milk-free diet and in the father's circulation while he was on an ...
M Y, Wang, J F, Desforges
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Clonogenic Cell Survival Assay
2005The clonogenic cell survival assay determines the ability of a cell to proliferate indefinitely, thereby retaining its reproductive ability to form a large colony or a clone. This cell is then said to be clonogenic. A cell survival curve is therefore defined as a relationship between the dose of the agent used to produce an insult and the fraction of ...
Anupama, Munshi +2 more
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Cell Survival and Plating Efficiency
Radiation Research, 1987The question of whether cellular radiation sensitivity is independent or related to plating efficiency (PE) is addressed. Three different cell lines, one human and mortal (AG 1522), one rodent and immortal (CHO AA8), and one rodent and mortal (C3H 10T1/2), were investigated. The first two showed a strong correlation between radiation sensitivity and PE,
D J, Brenner +3 more
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2002
The development of assays for measuring the survival of individual tumor cells revolutionized the study of experimental cancer therapy by enabling researchers to move from assessing the gross responses of tumors to measuring the survival of cells in the critical, clonogenic tumor-cell populations (1).
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The development of assays for measuring the survival of individual tumor cells revolutionized the study of experimental cancer therapy by enabling researchers to move from assessing the gross responses of tumors to measuring the survival of cells in the critical, clonogenic tumor-cell populations (1).
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Plasma cell development and survival
Immunological Reviews, 2010Summary: Plasma cells have long been recognized as the basis of humoral immunity, yet we are only now beginning to appreciate the complexities of plasma cell development and the fact that not all plasma cells are created equal. In vivo, plasma cells can arise from two developmental routes: one occurring outside the follicle and another within the ...
Sarah A, Oracki +4 more
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Cell Death and Survival Assays
2017Heat shock proteins are well-known protectors from cell death. Cell death (in particular, apoptosis and necrosis) is accompanied by certain hallmarks manifested as specific alterations in cellular membranes, cytoplasm, nucleus, and mitochondria. Some of those hallmarks are easily detectable in situ and, therefore, they can be applied for the assessment
Alexander E, Kabakov, Vladimir L, Gabai
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A molecular theory of cell survival
Physics in Medicine & Biology, 1973A theory is presented to explain the effect of radiation on cell survival. The theory is based on the assumption that a double strand break in the DXA helix is the critical damage. The theory is derived from the radiation induced molecular bond breaks in the DNA strands and parameters are included to take account of various repair processes which may ...
K H, Chadwick, H P, Leenhouts
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