Results 1 to 10 of about 2,050,369 (162)

Adults Myelodysplastic Syndromes in Algeria: A Study by the Algerian MDS Group

Asian Pacific Journal of Cancer Biology, 2023
Introduction: Myelodysplastic syndromes (MDS) are a group of haematological disorders, whose diagnosis is based mainly on cytological studies of blood and marrow cells and cytogenetic analysis.
Mohamed Amine Bekadja, Pierre Fenaux, Sabrina Akrouf, Redhouane Ahmed-Nacer, Rose-marie Hamladji, Amina Bouchakour, Souad Taoussi, Mohand Tahar Abad, Mohamed Bradai, Brahim Benzineb, Naima Mesli, M Cheritti, Z Zouaoui, Mohamed Benlazar, Soraya Bougherira, Fatiha Grifi, Hocine Ait-Ali, Malika allouda, Malika Djillali, Khadija Djouadi, Fatima Kherbache, Selma Hamdi, Hakim Hamouda, Imene Boumeida, Meriem Belhani, Nadia Boudjerra, Fatima Zohra Kaci, Soufi Osmani, Nabil Yafour, Soumia Barkat, Fatma Soltani, Razika Nacib, Mahdia Saidi, Laid Touati, Noureddine Lakhdari, Samira Zouani, Hadj Touhami, Djamel Saidi, Lamia Cherif Louazani, Mohamed Ramaoun, Cherifa Akkal, Nemra Mehalhal, Amina Krim, Noureddine Sidimansour, Zohra Ouchenane, Nadia Zidani, Salim Nekkal, Samia Barkat, Y Ouarlent, Mohamed Aberkane, Salah Eddine Belakehal, Aissa Bachiri, Samir Baghdad   +52 more
doaj   +1 more source

Characterization of Human-Induced Neural Stem Cells and Derivatives following Transplantation into the Central Nervous System of a Nonhuman Primate and Rats

Stem Cells International, 2022
Neural stem cells (NSCs) and derivatives are potential cellular sources to treat neurological diseases. In the current study, we reprogrammed human peripheral blood mononuclear cells into induced NSCs (iNSCs) and inserted GFP gene into the AAVS1 site for
Mengjia Li, Zhengbo Wang, Tianqi Zheng, Tianzhuang Huang, Baoguo Liu, Deqiang Han, Sumei Liu, Bochao Liu, Mo Li, Wei Si, Y. Alex Zhang, Yuyu Niu, Zhiguo Chen   +12 more
doaj   +1 more source

Enhanced therapeutic effects of mesenchymal stem cell-derived extracellular vesicles within chitosan hydrogel in the treatment of diabetic foot ulcers

Journal of Materials Science: Materials in Medicine, 2023
Extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (hUCMSCs) have emerged as promising candidates for cell-free therapy in various diseases, including chronic cutaneous wounds.
Shuangshuang Yang, Siyu Chen, Chengpeng Zhang, Jing Han, Chunyuan Lin, Xiaohui Zhao, Huizhen Guo, Yi Tan   +7 more
doaj   +1 more source

Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cells (MSCs) activate the endogenous immune regulatory system, inducing a therapeutic effect in recipients. MSCs have demonstrated the ability to modulate the differentiation of myeloid cells toward a phagocytic and anti ...
Maitane Ortiz-Virumbrales, Ramón Menta, Laura M. Pérez, Ornella Lucchesi, Pablo Mancheño-Corvo, Álvaro Avivar-Valderas, Itziar Palacios, Angel Herrero-Mendez, Wilfried Dalemans, Olga de la Rosa, Eleuterio Lombardo   +10 more
doaj   +1 more source

Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality

Scientific Reports, 2023
Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell therapies.
Nadine von Auw, Robert Serfling, Reni Kitte, Nadja Hilger, Chengkang Zhang, Clara Gebhardt, Anna Duenkel, Paul Franz, Ulrike Koehl, Stephan Fricke, U. Sandy Tretbar   +10 more
doaj   +1 more source

DC-CTL targeting carbonic anhydrase IX gene combined with iAPA therapy in the treatment of renal cell carcinoma

Human Vaccines & Immunotherapeutics, 2021
Introduction To deliver specific antigens in tumor immunotherapy, tumor cell lysates are commonly used to sensitize dendritic cells (DCs). However, the lysates possess low immunogenicity and contain many types of non-tumor-related antigens, which may ...
Heran Ma, Yi Tan, Dingke Wen, Na Qu, Qunfang Kong, Kun Li, Suxia Ma, Jianhui Zhang   +7 more
doaj   +1 more source

Phosphate restriction using a processed clay mineral reduces vascular pathologies and microalbuminuria in rats with chronic renal failure

BMC Nephrology, 2022
Background The progression of chronic kidney disease (CKD) is associated with an increasing risk of cardiovascular morbidity and mortality due to elevated serum phosphate levels.
Jacqueline Hofrichter, Kai Sempert, Claus Kerkhoff, Anne Breitrück, Reinhold Wasserkort, Steffen Mitzner   +5 more
doaj   +1 more source

The effect of platelet lysate in culture of PDLSCs: an in vitro comparative study [PDF]

PeerJ, 2019
Background Cellular therapy clinical applications require large-scale production of stem cells. Therefore, abundance, ease of isolation, and proliferative potential are the most important factors in choosing the appropriate source of cells for ...
Duaa A. Abuarqoub, Nazneen Aslam, Raghda B. Barham, Nidaa A. Ababneh, Diana A. Shahin, Abdallah A. Al-oweidi, Hanan D. Jafar, Mazin A. Al-Salihi, Abdalla S. Awidi   +8 more
doaj   +2 more sources

Differences and similarities between cancer and somatic stem cells: therapeutic implications

Stem Cell Research & Therapy, 2020
Over the last decades, the cancer survival rate has increased due to personalized therapies, the discovery of targeted therapeutics and novel biological agents, and the application of palliative treatments.
Fiorella Rossi, Hunter Noren, Richard Jove, Vladimir Beljanski, Karl-Henrik Grinnemo   +4 more
doaj   +1 more source

Near infra-red labelling and tracking of corneal endothelial cells in-vivo

Scientific Reports, 2022
Following corneal transplantation, there is an initial, rapid decline in corneal endothelial cells (CECs) following surgery. Direct imaging of post-transplantation endothelial cells is only possible weeks after surgery and with a limited field of view ...
Maninder Bhogal, Heng-Pei Ang, Shu-Jun Lin, Chan N. Lwin, Khadijah Adnan, Gary Peh, Jodhbir S. Mehta   +6 more
doaj   +1 more source