Results 11 to 20 of about 2,117,768 (268)

DC-CTL targeting carbonic anhydrase IX gene combined with iAPA therapy in the treatment of renal cell carcinoma

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Introduction To deliver specific antigens in tumor immunotherapy, tumor cell lysates are commonly used to sensitize dendritic cells (DCs). However, the lysates possess low immunogenicity and contain many types of non-tumor-related antigens, which may ...
Heran Ma   +7 more
doaj   +1 more source

Phosphate restriction using a processed clay mineral reduces vascular pathologies and microalbuminuria in rats with chronic renal failure

open access: yesBMC Nephrology, 2022
Background The progression of chronic kidney disease (CKD) is associated with an increasing risk of cardiovascular morbidity and mortality due to elevated serum phosphate levels.
Jacqueline Hofrichter   +5 more
doaj   +1 more source

The effect of platelet lysate in culture of PDLSCs: an in vitro comparative study [PDF]

open access: yesPeerJ, 2019
Background Cellular therapy clinical applications require large-scale production of stem cells. Therefore, abundance, ease of isolation, and proliferative potential are the most important factors in choosing the appropriate source of cells for ...
Duaa A. Abuarqoub   +8 more
doaj   +2 more sources

Cell Therapy: Replacement [PDF]

open access: yesStroke, 2003
Not long ago, the ability of the brain to restore function through regeneration of neural elements was thought to be nonexistent. It is now known that not only does some regenerative capacity exist, but implanted cells can integrate into the host brain, survive, and reverse neurological deficits.
Lawrence R, Wechsler   +1 more
openaire   +2 more sources

Cell therapy for stroke [PDF]

open access: yesNeurotherapeutics, 2004
Increasing experimental evidence suggests that cell transplantation can enhance recovery from stroke in animal models of focal cerebral ischemia. Clinical trials have been investigating the effects of a human immortalized neuronal cell line and porcine fetal neurons in stroke victims with persistent and stable deficits. Preclinical studies are focusing
Sean I, Savitz   +4 more
openaire   +2 more sources

Differences and similarities between cancer and somatic stem cells: therapeutic implications

open access: yesStem Cell Research & Therapy, 2020
Over the last decades, the cancer survival rate has increased due to personalized therapies, the discovery of targeted therapeutics and novel biological agents, and the application of palliative treatments.
Fiorella Rossi   +4 more
doaj   +1 more source

Cell therapy for cartilage repair [PDF]

open access: yesEmerging Topics in Life Sciences, 2021
Regenerative medicine, using cells as therapeutic agents for the repair or regeneration of tissues and organs, offers great hope for the future of medicine. Cell therapy for treating defects in articular cartilage has been an exemplar of translating this technology to the clinic, but it is not without its challenges. These include applying regulations,
Charlotte H. Hulme   +6 more
openaire   +3 more sources

Near infra-red labelling and tracking of corneal endothelial cells in-vivo

open access: yesScientific Reports, 2022
Following corneal transplantation, there is an initial, rapid decline in corneal endothelial cells (CECs) following surgery. Direct imaging of post-transplantation endothelial cells is only possible weeks after surgery and with a limited field of view ...
Maninder Bhogal   +6 more
doaj   +1 more source

Prevalence of human pegivirus-1 and sequence variability of its E2 glycoprotein estimated from screening donors of fetal stem cell-containing material

open access: yesVirology Journal, 2017
Background Human pegivirus-1 (HPgV-1) is a member of the Flaviviridae family whose genomic organization and mode of cellular entry is similar to that of hepatitis C virus (HCV).
Yakov Vitrenko   +3 more
doaj   +1 more source

Cell therapy of burns [PDF]

open access: yesCell Proliferation, 2011
AbstractSevere burns remain a life‐threatening local and general inflammatory condition often with serious sequelae, despite remarkable progress in their treatment over the past three decades. Cultured epidermal autografts, the first and still most up‐to‐date cell therapy for burns, plays a key role in that progress, but drawbacks to this need to be ...
T, Leclerc   +10 more
openaire   +2 more sources

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