Results 21 to 30 of about 2,117,768 (268)

Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine

open access: yesPlatelets, 2021
Platelet-rich plasma (PRP) has seen increased interest and utilization over the past decade, particularly in the field of musculoskeletal disease. This growth has been accompanied by the development of medical devices to realize PRP preparation which ...
Jeremy Magalon   +8 more
doaj   +1 more source

The 3Rs of Cell Therapy [PDF]

open access: yesStem Cells Translational Medicine, 2016
Abstract The 3Rs for a good education are “reading, 'riting, and 'rithmetic.” The basis for good health care solutions for the emergent field of cell therapy in the future will also involve 3Rs: regulation, reimbursement, and realization of value. The business models in this new field of cell therapy will involve these 3Rs.
Caplan, AI, Mason, C, Reeve, B
openaire   +3 more sources

Evaluation of Nonviral piggyBac and lentiviral Vector in Functions of CD19chimeric Antigen Receptor T Cells and Their Antitumor Activity for CD19+ Tumor Cells

open access: yesFrontiers in Immunology, 2022
Nonviral transposon piggyBac (PB) and lentiviral (LV) vectors have been used to deliver chimeric antigen receptor (CAR) to T cells. To understand the differences in the effects of PB and LV on CAR T-cell functions, a CAR targeting CD19 was cloned into PB
Zhicai Lin   +17 more
doaj   +1 more source

Potential solutions for manufacture of CAR T cells in cancer immunotherapy

open access: yesNature Communications, 2022
CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the ...
Ulrich Blache   +4 more
doaj   +1 more source

Do high-volume centers really save more lives? A call for scientific rigor and transparency. Response to Comment on: Does size matter? Center-specific characteristics and survival after allogeneic hematopoietic cell transplantation for acute myeloid leukemia: an analysis of the German Registry for Stem Cell Transplantation and Cell Therapy

open access: yesHaematologica
Not available.
Wolfgang Bethge   +2 more
doaj   +1 more source

Fetal Tissues Tested for Microbial Sterility by Culture- and PCR-Based Methods Can be Safely Used in Clinics

open access: yesCell Transplantation, 2017
Cell preparations to be used in clinical practice must be free of infectious agents. Safety concerns are especially elevated upon the use of human fetal tissues, which are otherwise highly advantageous in cell therapy.
Yakov Vitrenko   +5 more
doaj   +1 more source

Identification of very early inflammatory markers in a porcine myocardial infarction model

open access: yesBMC Veterinary Research, 2019
Background Acute myocardial infarction (AMI) is one of the most deleterious conditions leading to cardiovascular diseases and mortality. The importance of an early and accurate diagnosis assures immediate medical treatments, which are fundamental to ...
Esther López   +10 more
doaj   +1 more source

Potential and challenges of specifically isolating extracellular vesicles from heterogeneous populations

open access: yesScientific Reports, 2021
Extracellular vesicles (EVs) have attracted interest due to their ability to provide diagnostic information from liquid biopsies. Cells constantly release vesicles divers in size, content and features depending on the biogenesis, origin and function ...
Susann Allelein   +6 more
doaj   +1 more source

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