Results 11 to 20 of about 2,050,369 (162)

Cell Therapy: Replacement [PDF]

Stroke, 2003
Not long ago, the ability of the brain to restore function through regeneration of neural elements was thought to be nonexistent. It is now known that not only does some regenerative capacity exist, but implanted cells can integrate into the host brain, survive, and reverse neurological deficits.
Lawrence R, Wechsler, Douglas, Kondziolka   +1 more
openaire   +2 more sources

Cell therapy for cystinosis [PDF]

Nephrology Dialysis Transplantation, 2010
In the September 2009 issue of Blood, Syres et al. [1] report on syngeneic bone marrow cell (BMC) and haematopoietic stem cell (HSC) therapy as a successful treatment in a mouse model of cystinosis, an autosomal recessive metabolic disease caused by a defect in the transport of cystine across the lysosomal membrane. The accumulation of cystine crystals
Terryn, Sara, Devuyst, Olivier, Antignac, Corinne   +2 more
openaire   +3 more sources

Cell sheets in cell therapies [PDF]

Cytotherapy, 2018
This review aims to provide a broad introduction to the use of cell sheets and the role of materials in the delivery of cell sheets to patients within a clinical setting. Traditionally, cells sheets have been, and currently are, fabricated using established and accepted cell culture methods within standard formats (e.g., petri dishes) utilizing ...
Giles T.S. Kirby, Andrew Michelmore, Louise E. Smith, Jason D. Whittle, Robert D. Short   +4 more
openaire   +4 more sources

Prevalence of human pegivirus-1 and sequence variability of its E2 glycoprotein estimated from screening donors of fetal stem cell-containing material

Virology Journal, 2017
Background Human pegivirus-1 (HPgV-1) is a member of the Flaviviridae family whose genomic organization and mode of cellular entry is similar to that of hepatitis C virus (HCV).
Yakov Vitrenko, Iryna Kostenko, Kateryna Kulebyakina, Khrystyna Sorochynska   +3 more
doaj   +1 more source

Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine

Platelets, 2021
Platelet-rich plasma (PRP) has seen increased interest and utilization over the past decade, particularly in the field of musculoskeletal disease. This growth has been accompanied by the development of medical devices to realize PRP preparation which ...
Jeremy Magalon, Thibault Brandin, Pauline Francois, Clara Degioanni, Lucille De Maria, Fanny Grimaud, Julie Veran, Francoise Dignat-George, Florence Sabatier   +8 more
doaj   +1 more source

Antiviral T‐cell therapy

Immunological Reviews, 2014
SummarySerious viral infections are a common cause of morbidity and mortality after allogeneic stem cell transplantation. They occur in the majority of allograft recipients and are fatal in 17–20%. These severe infections may be prolonged or recurrent and add substantially to the cost, both human and financial, of the procedure.
Leen, Ann M., Heslop, Helen E., Brenner, Malcolm K.   +2 more
openaire   +3 more sources

Cell memory‐based therapy [PDF]

Journal of Cellular and Molecular Medicine, 2015
AbstractCurrent cell therapies, despite all of the progress in this field, still faces major ethical, technical and regulatory hurdles. Because these issues possibly stem from the current, restricted, stereotypical view of cell ultrastructure and function, we must think radically about the nature of the cell.
openaire   +2 more sources

Potential solutions for manufacture of CAR T cells in cancer immunotherapy

Nature Communications, 2022
CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the ...
Ulrich Blache, Georg Popp, Anna Dünkel, Ulrike Koehl, Stephan Fricke   +4 more
doaj   +1 more source

Evaluation of Nonviral piggyBac and lentiviral Vector in Functions of CD19chimeric Antigen Receptor T Cells and Their Antitumor Activity for CD19+ Tumor Cells

Frontiers in Immunology, 2022
Nonviral transposon piggyBac (PB) and lentiviral (LV) vectors have been used to deliver chimeric antigen receptor (CAR) to T cells. To understand the differences in the effects of PB and LV on CAR T-cell functions, a CAR targeting CD19 was cloned into PB
Zhicai Lin, Xiangzhen Liu, Tao Liu, Haixia Gao, Sitong Wang, Xingli Zhu, Lijie Rong, Jingbo Cheng, Zhigang Cai, Fu Xu, Xue Tan, Linjie Lv, Zhong Li, Zhong Li, Yan Sun, Qijun Qian, Qijun Qian, Qijun Qian   +17 more
doaj   +1 more source

Do high-volume centers really save more lives? A call for scientific rigor and transparency. Response to Comment on: Does size matter? Center-specific characteristics and survival after allogeneic hematopoietic cell transplantation for acute myeloid leukemia: an analysis of the German Registry for Stem Cell Transplantation and Cell Therapy

Haematologica
Not available.
Wolfgang Bethge, Peter Dreger, German Working Group for Hematopoietic Stem Cell Transplantation and Cellular Therapy e.V. (DAG-HSZT) - German Registry for Hematopoietic Stem Cell Transplantation and Cell Therapy (DRST)   +2 more
doaj   +1 more source