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Canadian Journal of Physiology and Pharmacology, 2012
Cell therapy is emerging as a new strategy to circumvent the adverse effects of heart disease. Many experimental and clinical studies investigating the transplantation of cells into the injured myocardium have yielded promising results. Moreover, data from these reports show that transplanted stem cells can engraft within the myocardium, differentiate
Abdelli, Latifa S. +3 more
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Cell therapy is emerging as a new strategy to circumvent the adverse effects of heart disease. Many experimental and clinical studies investigating the transplantation of cells into the injured myocardium have yielded promising results. Moreover, data from these reports show that transplanted stem cells can engraft within the myocardium, differentiate
Abdelli, Latifa S. +3 more
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Cell therapies for glioblastoma
Expert Opinion on Biological Therapy, 2006Malignant gliomas, including the most devastating type, glioblastoma multiforme (GBM), are characterised by their local growth and aggressive infiltration of the normal brain. GBMs result in a profound disability, leading to death in almost all cases. There has been little improvement in outcome despite intensive clinical and laboratory research during
Terzis, A Jorge A +4 more
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1996
Peripheral blood has replaced bone marrow as a source of hematopoietic stem cells for autologous rescue after high‐dose chemotherapy. Patients who receive peripheral blood stem cell (PBSC) transplants experience rapid and sustained hematopoietic reconstitution.
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Peripheral blood has replaced bone marrow as a source of hematopoietic stem cells for autologous rescue after high‐dose chemotherapy. Patients who receive peripheral blood stem cell (PBSC) transplants experience rapid and sustained hematopoietic reconstitution.
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2007
T cell therapies are increasingly used for the treatment of malignancies and viral-associated diseases. Initial studies focused on the use of unmanipulated T cell populations after allogeneic stem cell transplantation. More recently, the use of antigen-specific T cells has been explored.
S, Gottschalk +8 more
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T cell therapies are increasingly used for the treatment of malignancies and viral-associated diseases. Initial studies focused on the use of unmanipulated T cell populations after allogeneic stem cell transplantation. More recently, the use of antigen-specific T cells has been explored.
S, Gottschalk +8 more
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Stem Cell and Precursor Cell Therapy
NeuroMolecular Medicine, 2002Strategies for cell replacement therapy have been guided by the success in the hematopoietic stem cell field. In this review, we discuss the basis of this success and examine whether this stem cell transplant model can be replicated in other systems where stem cell therapy is being evaluated.
Jingli, Cai, Mahendra S, Rao
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Cell therapy commercialisation
2012‘Cells as therapies’ is a major step change in healthcare. Living cells offer solutions for a range of currently incurable medical conditions; however, both the technology and its essential infrastructure are far from market ready. Despite the limitations of any fledgling technology, the global cell therapy industry (CTI) has already achieved a billion-
Brindley, D, Mason, C
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Expert Opinion on Biological Therapy, 2008
Management of chronic pain remains a challenge in spite of numerous drugs that are either approved or still in development. Apart from inadequate relief, there are concerns about adverse effects and addiction. Cell therapy is being explored for relief of pain.To address the rationale for cell therapy for treatment of pain and its advantages over ...
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Management of chronic pain remains a challenge in spite of numerous drugs that are either approved or still in development. Apart from inadequate relief, there are concerns about adverse effects and addiction. Cell therapy is being explored for relief of pain.To address the rationale for cell therapy for treatment of pain and its advantages over ...
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Pluripotent Stem Cells for Cell Therapy
2021In an increasingly geriatric population, in which elderly people frequently face chronic diseases and degenerative conditions, cell therapies as part of novel regenerative medicine approaches are of great interest. Even though today's cell therapies mostly rely on adult stem cells like the mesenchymal stem cells or primary somatic cells, pluripotent ...
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Science, 2018
Synthetic Notch receptors expand the therapeutic potential of engineered T ...
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Synthetic Notch receptors expand the therapeutic potential of engineered T ...
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Blood, 2012
In this issue of Blood , Follenzi and colleagues demonstrate that transplantation of the bone marrow cells into hemophilia A mice partially restored factor VIII (FVIII) production and protected hemophilia A mice from bleeding challenge. 1 Surprisingly, in recipient hemophilia A mice, the donor BM-derived hepatocytes or endothelial cells were rare ...
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In this issue of Blood , Follenzi and colleagues demonstrate that transplantation of the bone marrow cells into hemophilia A mice partially restored factor VIII (FVIII) production and protected hemophilia A mice from bleeding challenge. 1 Surprisingly, in recipient hemophilia A mice, the donor BM-derived hepatocytes or endothelial cells were rare ...
openaire +2 more sources