Results 21 to 30 of about 3,286,390 (370)

Near infra-red labelling and tracking of corneal endothelial cells in-vivo

Scientific Reports, 2022
Following corneal transplantation, there is an initial, rapid decline in corneal endothelial cells (CECs) following surgery. Direct imaging of post-transplantation endothelial cells is only possible weeks after surgery and with a limited field of view ...
Maninder Bhogal, Heng-Pei Ang, Shu-Jun Lin, Chan N. Lwin, Khadijah Adnan, Gary Peh, Jodhbir S. Mehta   +6 more
doaj   +1 more source

Interleukin-2 therapy in patients with HIV infection [PDF]

, 2009
BACKGROUND Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone. The clinical implication of these increases is not known.
Aagaard, B., Abrams, D., Angus, B., Aragon, E., Arnaiz, J., Babiker, A., Borup, L., Clotet, B., Collins, G., Cooper, D. A., Cordwell, B., Darbyshire, J., Dodds, W., Dragsted, U., Emery, S., Fau, A., Fleck, S., Fox, L., Gey, D., Gordin, F., Grarup, J., Grijsen, M., Hengge, U., Herrero, P., Jansson, P., Jensen, B., Jensen, K., Juncher, H., Lane, H. C., Lange, J., Langebeek, N., Lopez, P., Losso, M. H., Lundgren, J., Lundgren, J. D., Lévy, Y., Matthews, C., Mitsuyasu, R., Mollerup, D., Neaton, J. D., Pearson, M., Phillips, A., Reilev, S., Reiss, P., Routy, J. P., Tambussi, G., Tillmann, K., van der Horst, C., Varea, S., Wentworth, D.   +49 more
core   +5 more sources

Mathematical deconvolution of CAR T-cell proliferation and exhaustion from real-time killing assay data. [PDF]

, 2020
Chimeric antigen receptor (CAR) T-cell therapy has shown promise in the treatment of haematological cancers and is currently being investigated for solid tumours, including high-grade glioma brain tumours.
Abler, Daniel, Adhikarla, Vikram, Barish, Michael, Branciamore, Sergio, Brown, Christine E, Cho, Heyrim, Frankhouser, David, Gutova, Margarita, Machuca, Vanessa, Maestrini, Davide, Rockne, Russell C, Sahoo, Prativa, Wang, Dongrui, Yang, Xin   +13 more
core   +2 more sources

Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. [PDF]

, 2013
Controversy exists regarding the potential regenerative influences of incretin therapy on pancreatic β-cells versus possible adverse pancreatic proliferative effects.
Atkinson, Mark, Butler, Alexandra E, Butler, Peter C, Campbell-Thompson, Martha, Dawson, David W, Gurlo, Tatyana   +5 more
core   +2 more sources

Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells [PDF]

, 2016
Β-blockers (BB) are a primary treatment for chronic heart disease (CHD), resulting in prognostic and symptomatic benefits. Cardiac cell therapy represents a promising regenerative treatment and, for autologous cell therapy, the patients clinical history ...
ANGELINI, FRANCESCO, BARRETTA, ANTONIO, BIONDI ZOCCAI, GIUSEPPE, CAVARRETTA, Elena, CHIMENTI, ISOTTA, DE FALCO, ELENA, FRATI, GIACOMO, GRECO, Ernesto, MARULLO, Antonino, PAGANO, FRANCESCA, PERUZZI, MARIANGELA, SCIARRETTA, SEBASTIANO   +11 more
core   +1 more source

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]

, 2012
The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J., Plate, Karl H., Scholz, Alexander   +2 more
core   +1 more source

In Silico Implementation of Evolutionary Paradigm in Therapy Design: Towards Anti-Cancer Therapy as Darwinian Process [PDF]

Journal of Theoretical Biology 485(2020) 110038, 2018
In here presented in silico study we suggest a way how to implement the evolutionary principles into anti-cancer therapy design. We hypothesize that instead of its ongoing supervised adaptation, the therapy may be constructed as a self-sustaining evolutionary process in a dynamic fitness landscape established implicitly by evolving cancer cells ...
arxiv   +1 more source

Antiviral T‐cell therapy

Immunological Reviews, 2014
SummarySerious viral infections are a common cause of morbidity and mortality after allogeneic stem cell transplantation. They occur in the majority of allograft recipients and are fatal in 17–20%. These severe infections may be prolonged or recurrent and add substantially to the cost, both human and financial, of the procedure.
Helen E. Heslop, Malcolm K. Brenner, Ann M. Leen   +2 more
openaire   +4 more sources

Cholangiocytes: Cell transplantation [PDF]

, 2017
Background:Due to significant limitations to the access to orthotropic liver transplantation, cell therapies forliver diseases have gained large interest worldwide.Scope of review:To revise current literature dealing with cell therapy for liver diseases.
Alvaro, Domenico, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Ridola, Lorenzo   +5 more
core   +1 more source

Technical and biological review of authorized medical devices for platelets-rich plasma preparation in the field of regenerative medicine

Platelets, 2021
Platelet-rich plasma (PRP) has seen increased interest and utilization over the past decade, particularly in the field of musculoskeletal disease. This growth has been accompanied by the development of medical devices to realize PRP preparation which ...
Jeremy Magalon, Thibault Brandin, Pauline Francois, Clara Degioanni, Lucille De Maria, Fanny Grimaud, Julie Veran, Francoise Dignat-George, Florence Sabatier   +8 more
doaj   +1 more source