Results 31 to 40 of about 3,286,390 (370)
Translational aspects of cardiac cell therapy. [PDF]
, 2015 Cell therapy has been intensely studied for over a decade as a potential treatment for ischaemic heart disease. While initial trials using skeletal myoblasts, bone marrow cells and peripheral blood stem cells showed promise in improving cardiac function,
Ardehali, Reza +3 more
core +1 more source
Virology Journal, 2017 Background Human pegivirus-1 (HPgV-1) is a member of the Flaviviridae family whose genomic organization and mode of cellular entry is similar to that of hepatitis C virus (HCV).
Yakov Vitrenko +3 more
doaj +1 more source
Potential solutions for manufacture of CAR T cells in cancer immunotherapy
Nature Communications, 2022 CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the ...
Ulrich Blache +4 more
doaj +1 more source
Cell Therapy for Type 1 Diabetes [PDF]
, 2014 Acknowledgements The work described in this review was supported by a grant from the MRC. K.R.M. is supported by a fellowship from the Scottish Translational Medicines and Therapeutics Initiative through the Wellcome Trust.Peer reviewedPublisher ...
Docherty, H. M. +3 more
core +1 more source
Frontiers in Immunology, 2022 Nonviral transposon piggyBac (PB) and lentiviral (LV) vectors have been used to deliver chimeric antigen receptor (CAR) to T cells. To understand the differences in the effects of PB and LV on CAR T-cell functions, a CAR targeting CD19 was cloned into PB
Zhicai Lin +17 more
doaj +1 more source
Study of dose-dependent combination immunotherapy using engineered T cells and IL-2 in cervical cancer [PDF]
, 2020 Adoptive T cell based immunotherapy is gaining significant traction in cancer treatment. Despite its limited success, so far, in treating solid cancers, it is increasingly successful, demonstrating to have a broader therapeutic potential. In this paper we develop a mathematical model to study the efficacy of engineered T cell receptor (TCR) T cell ...
arxiv +1 more source
Cell Therapy in Dermatology [PDF]
Cold Spring Harbor Perspectives in Medicine, 2014 Harnessing the regenerative capacity of keratinocytes and fibroblasts from human skin has created new opportunities to develop cell-based therapies for patients. Cultured cells and bioengineered skin products are being used to treat patients with inherited and acquired skin disorders associated with defective skin, and further clinical trials of new ...
Petrof, Gabriela +2 more
openaire +4 more sources
Evolutionarily stable anti-cancer therapies by autologous cell defection [PDF]
, 2013 Game theory suggests an anti-cancer treatment based on the use of modified cancer cells that disrupt cooperation within the tumor. Cancer cells are harvested from the patient, the genes for the production of essential growth factors are knocked out in ...
Archetti, M.
core +1 more source
Mathematical Model of the Impact of Chemotherapy and Anti-Angiogenic Therapy on Drug Resistance in Glioma Growth [PDF]
arXiv, 2023 This research presents a mathematical model of glioma growth dynamics with drug resistance, capturing interactions among five cell populations: glial cells, sensitive glioma cells, resistant glioma cells, endothelial cells, and neuron cells, along with two therapy agent populations: chemotherapy and anti-angiogenic therapy.
arxiv
Tracking TCRß sequence clonotype expansions during antiviral therapy using high-throughput sequencing of the hypervariable region [PDF]
, 2016 To maintain a persistent infection viruses such as hepatitis C virus (HCV) employ a range of mechanisms that subvert protective T cell responses. The suppression of antigen-specific T cell responses by HCV hinders efforts to profile T cell responses ...
Arvind H Patel +10 more
core +3 more sources