Results 21 to 30 of about 1,036,044 (316)

Functional SARS-CoV-2-specific T cells of donor origin in allogeneic stem cell transplant recipients of a T-cell-replete infusion: A prospective observational study

Frontiers in Immunology, 2023
In the current post-pandemic era, recipients of an allogeneic hematopoietic stem cell transplant (HCT) deserve special attention. In these vulnerable patients, vaccine effectiveness is reduced by post-transplant immune-suppressive therapy; consequently ...
Corinna La Rosa, Flavia Chiuppesi, Yoonsuh Park, Qiao Zhou, Dongyun Yang, Ketevan Gendzekhadze, Minh Ly, Jing Li, Teodora Kaltcheva, Sandra Ortega Francisco, Miguel-Angel Gutierrez, Haris Ali, Salman Otoukesh, Idoroenyi Amanam, Amandeep Salhotra, Vinod A. Pullarkat, Ibrahim Aldoss, Michael Rosenzweig, Ahmed M. Aribi, Anthony S. Stein, Guido Marcucci, Sanjeet Singh Dadwal, Ryotaro Nakamura, Stephen J. Forman, Monzr M. Al Malki, Don J. Diamond   +25 more
doaj   +1 more source

Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]

, 2008
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H., Brockhoff, G., Christ, B., Jauch, Karl-Walter, Kirchner, S., Kunz-Schughart, L.A., Lichtenauer, M., Schlitt, H.-J., Stock, P., Thasler, Wolfgang E., Weiss, T.S.   +10 more
core   +1 more source

Robust SARS-COV-2-specific T-cell immune memory persists long-term in immunocompetent individuals post BNT162b2 double shot

Heliyon, 2022
Background: A robust efficiency of mRNA vaccines against coronavirus disease-2019 has been demonstrated, however, the intended long-term protection against SARS-CoV-2 has been challenged by the waning humoral and cellular immunity over time, leading to a
Anastasia Papadopoulou, Fani Stavridou, Maria Giannaki, Kiriaki Paschoudi, Fani Chatzopoulou, Eleni Gavriilaki, Grigorios Georgolopoulos, Achilles Anagnostopoulos, Evangelia Yannaki   +8 more
doaj   +1 more source

Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. [PDF]

, 2018
Injectable hydrogels with tunable physiochemical and biological properties are potential tools for improving neural stem/progenitor cell (NSPC) transplantation to treat central nervous system (CNS) injury and disease.
Czechanski, A, Deming, TJ, Kim, JH, O'Shea, TM, Reinholdt, LG, Sofroniew, MV, Wollenberg, AL   +6 more
core   +1 more source

FLT3-ITD Compared with DNMT3A R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study

Turkish Journal of Hematology, 2018
Objective: This study aimed to evaluate DNMT3A exon 23 mutations and their prognostic impacts in the presence of NPM1 and FLT3 mutations in acute myeloid leukemia (AML) patients who underwent allogeneic hematopoietic stem cell transplantation (HSCT ...
Majid Teremmahi Ardestani, Ahmad Kazemi, Bahram Chahardouli, Saeed Mohammadi, Mohsen Nikbakht, Shahrbano Rostami, Mahdi Jalili, Mohammad Vaezi, Kamran Alimoghaddam, Ardeshir Ghavamzadeh   +9 more
doaj   +1 more source

Donor Lymphocyte Infusion and Molecular Monitoring for Relapsed Myelofibrosis After Hematopoietic Cell Transplantation

HemaSphere, 2023
Hematopoietic cell transplantation (HCT) is a curative approach for myelofibrosis patients, but relapse is a major cause of treatment failure. We investigated the effect of donor lymphocyte infusion (DLI) in 37 patients with molecular (n = 17) or ...
Nico Gagelmann, Christine Wolschke, Anita Badbaran, Dietlinde Janson, Carolina Berger, Evgeny Klyuchnikov, Francis Ayuk, Boris Fehse, Nicolaus Kröger   +8 more
doaj   +1 more source

Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients [PDF]

, 2018
Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic ...
Angeletti, S, Annibali, O, Avvisati, G, Cantonetti, M, Circhetta, E, Franceschini, L, Piccioni, L, Riva, E., Rizzo, E, Sarlo, C, Scagnolari, C, Statzu, M, Tirindelli, Mc, Tomarchio, V   +13 more
core   +1 more source

Antibody response after vaccination against SARS-CoV-2 in adults with hematological malignancies: a systematic review and meta-analysis

Haematologica, 2021
Vaccines against SARS-CoV-2 have shown remarkable efficacy and thus constitute an important preventive option against coronavirus disease 2019 (COVID-19), especially in fragile patients.
Nico Gagelmann, Francesco Passamonti, Christine Wolschke, Radwan Massoud, Christian Niederwieser, Raissa Adjallé, Barbara Mora, Francis Ayuk, Nicolaus Kröger   +8 more
doaj   +1 more source

Chimerism after organ transplantation [PDF]

, 1997
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft.
Demetris, AJ, Fung, JJ, Murase, N, Rao, AS, Starzl, TE, Thomson, AW, Trucco, M   +6 more
core   +1 more source

Clonal Hematopoiesis at the Crossroads of Inflammatory Bowel Diseases and Hematological Malignancies: A Biological Link?

Frontiers in Oncology, 2022
Inflammatory bowel diseases (IBDs) are a group of chronic conditions of the gastrointestinal tract in which nationwide studies have revealed a higher risk of hematological malignancies (HMs).
Cosimo Cumbo, Francesco Tarantini, Antonella Zagaria, Luisa Anelli, Crescenzio Francesco Minervini, Nicoletta Coccaro, Giuseppina Tota, Luciana Impera, Elisa Parciante, Maria Rosa Conserva, Immacolata Redavid, Paola Carluccio, Mario Delia, Annamaria Giordano, Maria Chiara Longo, Tommasina Perrone, Antonella Russo Rossi, Giorgina Specchia, Pellegrino Musto, Francesco Albano   +19 more
doaj   +1 more source