Results 61 to 70 of about 12,548,510 (343)

Hitting the Wall—Sensing and Signaling Pathways Involved in Plant Cell Wall Remodeling in Response to Abiotic Stress

open access: yesPlants, 2018
Plant cells are surrounded by highly dynamic cell walls that play important roles regulating aspects of plant development. Recent advances in visualization and measurement of cell wall properties have enabled accumulation of new data about wall ...
Lazar Novakovic   +4 more
semanticscholar   +1 more source

Plant cell walls: Wall-associated kinases and cell expansion [PDF]

open access: yesCurrent Biology, 2001
Arabidopsis has a family of five cell wall-associated protein kinases (WAKs) with properties suggestive of transmembrane sensors between the cell wall and the cytoplasm. Recent results show that WAKs are bound to pectin and are necessary for normal leaf cell enlargement and other growth processes.
openaire   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Cell Wall Metabolism in Response to Abiotic Stress

open access: yesPlants, 2015
This review focuses on the responses of the plant cell wall to several abiotic stresses including drought, flooding, heat, cold, salt, heavy metals, light, and air pollutants.
H. Gall   +5 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Sentinels at the wall: cell wall receptors and sensors [PDF]

open access: yesNew Phytologist, 2007
SummaryThe emerging view of the plant cell wall is of a dynamic and responsive structure that exists as part of a continuum with the plasma membrane and cytoskeleton. This continuum must be responsive and adaptable to normal processes of growth as well as to stresses such as wounding, attack from pathogens and mechanical stimuli.
Daphne R. Goring   +2 more
openaire   +2 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Immunoreactivity of the fungal cell wall [PDF]

open access: yesMedical Mycology, 2001
The cell wall is the major fungal structure involved in the interaction with the host and most of the immunological effects observed with intact fungal cells have been reproduced with cell-wall components. As a result of the exposure to fungal antigens, most individuals develop both cellular and antibody responses intended to limit the invasiveness or ...
Miren Josu Omaetxebarria   +4 more
openaire   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment

open access: yesBMC Plant Biology, 2019
Background Plant cell walls participate in all plant-environment interactions. Maintaining cell wall integrity (CWI) during these interactions is essential.
Timo Engelsdorf   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy