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Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Malate matters: disrupting bacterial-type phosphoenolpyruvate carboxylase (BTPC) rewires tomato fruit development. [PDF]

Plant Physiol
Martínez Rivas FJ, Smith MA, Zangishei Z, Alseekh S, Usadel B, Plaxton WC, Fernie AR.   +6 more
europepmc   +1 more source

TMT Proteomics-Based Study of Proteins and Pathways Associated with β-Glucan Degradation in Barley Germination. [PDF]

Metabolites
Huang J, Ning F, Zhang G.
europepmc   +1 more source

Molecular mechanisms of plant hormones and sugars regulates strawberry fruit development and ripening. [PDF]

Plant Mol Biol
Pinto CA, Althaus HV, Coutrim RL, Ayub RA, Grimaldi F.   +4 more
europepmc   +1 more source

Reactive oxygen species in thoracic aortic dissection: Insights into mechanisms and disease progression. [PDF]

Redox Biol
Jiang M, Mo F, Cao G, Li S, Fu W, Wang L.   +5 more
europepmc   +1 more source

Molecular resilience: genetic analysis of multiple-stress tolerance (osmotic, salinity, cold and heat) during potato (<i>Solanum tuberosum</i> L.) microtuberization. [PDF]

Front Plant Sci
Herrera-Isidron L, Careaga-Rojas IA, Uribe-Lopez B, Navarro-Vega AM, Barraza A, Valencia-Lozano E, Cabrera-Ponce JL.   +6 more
europepmc   +1 more source

Interspecific secondary plasmodesmata at the parasitic interface. [PDF]

Plant Cell Physiol
Aoki K, Tsushima A.
europepmc   +1 more source

Cell wall deposition and metabolism in wheat grain

Journal of Cereal Science, 2012
There is an amazing diversity of cell wall composition and cell wall polysaccharide structure in wheat grain that is only partly explained by the complexity of plant tissues and cell type functions present in this organ. This review presents the state of the art on the structure and diversity of cell wall polymers in mature wheat grain and recent ...
Saulnier, Luc, Guillon, Fabienne, Chateigner Boutin, Anne Laure   +2 more
openaire   +4 more sources

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Bacterial metabolism and susceptibility to cell wall-active antibiotics

2023
Bacterial infections are increasingly resistant to antimicrobial therapy. Intense research focus has thus been placed on identifying the mechanisms that bacteria use to resist killing or growth inhibition by antibiotics and the ways in which bacteria share these traits with one another.
Megan Renee, Keller, Tobias, Dörr
openaire   +2 more sources