Results 21 to 30 of about 12,646,619 (273)

Neural networks on chemically patterned "cultured probe" electrode arrays: network growth and activity patterns [PDF]

open access: yes, 2003
A 'cultured probe' is a hybrid type of neural information transducer or prosthesis, for stimulation and/or recording of neural activity in the brain or the spinal cord (ventral motor region or dorsal sensory region).
Buul, B.R.M. van   +3 more
core   +3 more sources

Cells of Matter—In Vitro Models for Myotonic Dystrophy

open access: yesFrontiers in Neurology, 2018
Myotonic dystrophy type 1 (DM1 also known as Steinert disease) is a multisystemic disorder mainly characterized by myotonia, progressive muscle weakness and wasting, cognitive impairments, and cardiac defects. This autosomal dominant disease is caused by
Magdalena Matloka   +3 more
doaj   +1 more source

APOE4 dysregulates autophagy in cultured cells

open access: yesAutophagy Reports, 2022
Human APOE4 (apolipoprotein E4 isoform) is a powerful genetic risk factor for late-onset Alzheimer disease (AD). Many groups have investigated the effect of APOE4 on the degradation of amyloid β (Aβ), the main component of plaques found in the brains of ...
Gianna M. Fote, Joan S. Steffan
doaj   +1 more source

Homogenization of Mammalian Cultured Cells

open access: yesThe Scientific World Journal, 2002
Satisfactory homogenization of cultured cells is a necessary prerequisite to any fractionation schedule. Protocols are given for homogenization in iso-osmotic (A) and hypo-osmotic (B) media that should be broadly applicable to any cell type and to any ...
John Graham
doaj   +1 more source

Microsystems for Cell Cultures

open access: yesBiosensors, 2022
Microfabricated systems are increasingly being utilized in biotechnological, biomedical, and pharmaceutical research and development as replacements for traditional in vitro cell cultures, bioreactors, and animal experiments (Figure 1) [...]
openaire   +3 more sources

TRAIL-Mediated Apoptosis in Breast Cancer Cells Cultured as 3D Spheroids

open access: yesPLoS ONE, 2014
TNF-alpha-related-apoptosis-inducing-ligand (TRAIL) has been explored as a therapeutic drug to kill cancer cells. Cancer cells in the circulation are subjected to apoptosis-inducing factors.
Siddarth Chandrasekaran   +4 more
semanticscholar   +1 more source

Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries [PDF]

open access: yes, 2016
Aim: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDC) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix. Methods: Explants from equine
Dudhia, J   +3 more
core   +2 more sources

Distinct cell stress responses induced by ATP restriction in quiescent human fibroblasts

open access: yesFrontiers in Genetics, 2016
Quiescence is the prevailing state of many cell types under homeostatic conditions. Yet, surprisingly little is known about how quiescent cells respond to energetic and metabolic challenges.
Nirupama Yalamanchili   +5 more
doaj   +1 more source

Novel culture media enhances mononuclear cells from patients with chronic limb-threatening ischemia to increase vasculogenesis and anti-inflammatory effect

open access: yesStem Cell Research & Therapy, 2021
Background Quality and Quantity culture media (QQ culture media) was reported to enhance vasculogenesis and angiogenesis function of mononuclear cells (MNCs) from healthy volunteers.
Nuttapol Chruewkamlow   +11 more
doaj   +1 more source

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

open access: yesJournal of Clinical Investigation, 1989
Endothelium-derived relaxing factor has been recently identified as nitric oxide. The purpose of this study was to determine if vasodilator drugs that generate nitric oxide inhibit vascular smooth muscle mitogenesis and proliferation in culture.
U. Garg, A. Hassid
semanticscholar   +1 more source

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