Results 161 to 170 of about 341,348 (303)

Integrating regenerative biology with developmental psychobiology to understand behavioral recovery

Developmental psychobiology (DPB) is a sub-discipline of developmental biology investigating behavioral development. Regenerative biology is also a sub-discipline of developmental biology, studying how tissues and organs heal and regenerate after injury.
Justin Varholick
core   +1 more source

From germline immortality to somatic rejuvenation: Unlocking the ovarian blueprint for longevity. [PDF]

PLoS Biol
Chiavellini P, Sebastiano V.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

p68 RNA helicase - identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts

, 2014
The human p68 protein is an RNA-dependent ATPase and RNA helicase which was first identified because of its immunological cross-reaction with a viral RNA helicase, simian virus 40 large T antigen.
Jamieson, DJ, Lane, DP, MacNeill, Stuart Andrew, McPheat, J, Southgate, J, Iggo, RD   +5 more
core  

Conditions for establishing fin primary cell cultures in a wide range of ray-finned fishes

Ray-finned fishes (Actinopterygii) represent the most diverse vertebrate lineage that show extensive variations in physiology, ways of life, and adaptations to marine and freshwater environments, and several species have been established as biological ...
Venturelli, Natália Bortholazzi [UNESP], Climaco, João Pedro Silva [UNESP], do Nascimento Moreira, Camila [UNESP], Cardoso, Adauto Lima [UNESP], Martins, Cesar [UNESP], Oliveira, Jordana Inácio Nascimento [UNESP]   +5 more
core   +1 more source

Editorial: Expanding the glial frontiers: development, function and pathophysiology. [PDF]

Front Cell Neurosci
Kim DW.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

StPedf: Cell trajectory inference of spatial transcriptomics via spatial proximity embedding and spatial density-adaptive fusion. [PDF]

PLoS Comput Biol
Zhang Y, Sun Z, Shi Z, Nan M, Fu Y, Ren Q, Gao J.   +6 more
europepmc   +1 more source

GPI-AP release in cellular, developmental, and reproductive biology

GPI-AP release in cellular, developmental, and reproductive biology
Yoshitaka Fujihara, Masahito Ikawa, GPI-AP release in cellular, developmental, and reproductive biology, Journal of Lipid Research, Volume 57, Issue 4, 2016, Pages 538-545, ISSN 0022-2275, https://doi.org/10.1194/jlr.R063032. Glycosylphosphatidylinositol-anchored proteins (GPI-APs) contain a covalently linked GPI anchor located on outer cell membranes.
openaire