Results 11 to 20 of about 365,586 (305)

Whole body regeneration and developmental competition in two botryllid ascidians

open access: yesEvoDevo, 2021
Background Botryllid ascidians are a group of marine invertebrate chordates that are colonial and grow by repeated rounds of asexual reproduction to form a colony of individual bodies, called zooids, linked by a common vascular network.
Shane Nourizadeh   +4 more
doaj   +1 more source

Enhanced germline stem cell longevity in Drosophila diapause

open access: yesNature Communications, 2022
Drosophila enter adult reproductive diapause in low temperatures and short day, halting ovarian development yet preserving fertility. Here the authors show that ovarian arrest in diapause is distinct from other stress responses and that despite DNA ...
Sreesankar Easwaran   +3 more
doaj   +1 more source

Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion

open access: yesNature Communications, 2023
Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated
Hema M. Swasthi   +4 more
doaj   +1 more source

Coordinated Subcellular Organization in Bacteria

open access: yes, 2022
HonorsMolecular, Cellular, and Developmental Biology (MCDB)University of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/174732/1/yangsiny ...
Yang, Sinyu
core   +1 more source

Misregulation of Nucleoporins 98 and 96 leads to defects in protein synthesis that promote hallmarks of tumorigenesis

open access: yesDisease Models & Mechanisms, 2022
Nucleoporin 98KD (Nup98) is a promiscuous translocation partner in hematological malignancies. Most disease models of Nup98 translocations involve ectopic expression of the fusion protein under study, leaving the endogenous Nup98 loci unperturbed ...
Ajai J. Pulianmackal   +6 more
doaj   +1 more source

The cellular and developmental biology of medulloblastoma: Current perspectives on experimental therapeutics [PDF]

open access: yesCancer Biology & Therapy, 2010
Dysregulation of various signaling pathways that govern cerebellar development with respect to cell proliferation, growth arrest, apoptosis and differentiation has been postulated to contribute to medulloblastoma tumourigenesis. This review will highlight the unique nature of cerebellar development in terms of its derivation from two germinal matrices ...
Vinit Krishna, Srivastava   +1 more
openaire   +2 more sources

GIGANTEA recruits the UBP12 and UBP13 deubiquitylases to regulate accumulation of the ZTL photoreceptor complex

open access: yesNature Communications, 2019
The daily accumulation of the ZEITLUPE (ZTL) photoreceptor/E3 ubiquitin ligase relies on a light-dependent interaction with GIGANTEA (GI). Here the authors show that GI recruits two deubiquitylases to help stabilize the ZTL-GI complex during the day and ...
Chin-Mei Lee   +5 more
doaj   +1 more source

Lithium-sensing riboswitch classes regulate expression of bacterial cation transporter genes

open access: yesScientific Reports, 2022
Lithium is rare in Earth’s crust compared to the biologically relevant alkali metal cations sodium and potassium but can accumulate to toxic levels in some environments.
Neil White   +4 more
doaj   +1 more source

International plant molecular biology: a bright future for green science [PDF]

open access: yes, 2012
Sibum Sung, Enamul Huq and Z Jeffrey Chen* Author Affiliations Section of Molecular Cell and Developmental Biology, Center for Computational Biology and Bioinformatics, and Institute for Cellular and Molecular Biology, The University of Texas at ...
Sung, Sibum   +2 more
core   +1 more source

Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function

open access: yesNature Communications, 2017
Multiple mechanisms regulate Wnt/ß-catenin signalling. Zhanget al. describe a novel regulatory pathway and show that the activator of canonical Wnt signalling, Norrin, triggers endocytosis of its receptor Frizzled4 by promoting Frizzled4 ubiquitination.
Chi Zhang   +5 more
doaj   +1 more source

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