Results 181 to 190 of about 1,916,376 (328)

Droplet-Based Cytotoxicity Assay: Implementation of Time-Efficient Screening of Antitumor Activity of Natural Killer Cells

ACS Omega, 2020
Silvia Antona, Ilia Platzman, Joachim P. Spatz   +2 more
doaj   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

European Biophysics Journal - Special Issue Celebrating the 70th Anniversary of the Institute of Biophysics, Czech Academy of Sciences. [PDF]

Eur Biophys J
Kovařík A, Hof M, Bártová E.
europepmc   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

Advanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju, Roshan Velluvakandy, Xianghua Wu, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Kamila Bendíčková, Jan Frič, Martin Pumera   +7 more
wiley   +1 more source

Biophysics in the Czech Republic: 70th anniversary of the institute of biophysics. [PDF]

Eur Biophys J
Bártová E, Kozubek S, Kovařík A.
europepmc   +1 more source

Modeling Biophysical Mechanisms underlying Cellular Homeostasis

, 2010
Cellular homeostasis is the effort of all living cells to maintain their intracellular content when facing physiological change(s) in the extracellular environment. To date, cellular homeostasis is known to be regulated mainly by time-consuming active mechanisms and via multiple signaling pathways within the cells.
openaire   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Author Correction: Reconstitution of contractile actomyosin rings in vesicles

Nature Communications, 2022
Thomas Litschel, Charlotte F. Kelley, Danielle Holz, Maral Adeli Koudehi, Sven K. Vogel, Laura Burbaum, Naoko Mizuno, Dimitrios Vavylonis, Petra Schwille   +8 more
doaj   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

Advanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam, Jiao Zhai, Heng Zou, Yu Chen, Michael Yang   +4 more
wiley   +1 more source

Evaluation of Acoustophoretic and Dielectrophoretic Forces for Droplet Injection in Droplet-Based Microfluidic Devices

ACS Omega
Jacqueline A. De Lora, Florian Aubermann, Christoph Frey, Timotheus Jahnke, Yuanzhen Wang, Sebastian Weber, Ilia Platzman, Joachim P. Spatz   +7 more
doaj   +1 more source