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Pulsed Feedback Defers Cellular Differentiation [PDF]

open access: yesPLoS Biology, 2012
Environmental signals induce diverse cellular differentiation programs. In certain systems, cells defer differentiation for extended time periods after the signal appears, proliferating through multiple rounds of cell division before committing to a new ...
A Chastanet   +56 more
core   +10 more sources

Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size

open access: yesScientific Reports, 2022
Cryopreservation of rare plant materials is an important approach for preserving germplasms and is a good added concept to tissue banking. The preservation of embryogenic cell suspensions is even more valuable as the tissues facilitate in producing ...
A. Mujib   +2 more
doaj   +1 more source

Elicitation Induced α-Amyrin Synthesis in Tylophora indica In Vitro Cultures and Comparative Phytochemical Analyses of In Vivo and Micropropagated Plants

open access: yesPlants, 2023
Tylophora indica (Burm. f.) Merrill is an endangered medicinal plant that possesses various active agents, such as tylophorinine, kaempferol, quercetin, α-amyrin and beta-sitosterol, with multiple medicinal benefits.
Jyoti Mamgain   +7 more
doaj   +1 more source

Preparation and Low Temperature Short-term Storage for Synthetic Seeds of Caladium bicolor

open access: yesNotulae Scientia Biologicae, 2015
An efficient somatic embryo encapsulation and in vitro plant regeneration technique were established with Caladium bicolor, an important ornamental plant.Tuber derived embryogenic callus (95.50%) was obtained on Murashige and Skoog (MS) medium amended ...
Mehpara MAQSOOD   +2 more
doaj   +3 more sources

Methyl Jasmonate Elicitation for In Vitro Lycorine Accumulation in Three Zephyranthes Species and Comparative Analysis of Tissue-Cultured and Field Grown Plants

open access: yesHorticulturae, 2023
Lycorine is an important Amaryllidaceae alkaloid showing anti-cancerous activity on numerous cell lines; and it also demonstrates antiviral activity against several viruses including SARS-CoV-2 responsible for COVID-19.
Rukaya Syeed   +8 more
doaj   +1 more source

Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System. [PDF]

open access: yes, 2017
Monitoring pluripotent stem cell behaviors (self-renewal and differentiation to specific lineages/phenotypes) is critical for a fundamental understanding of stem cell biology and their translational applications.
Horner, Christopher B   +7 more
core   +6 more sources

LAMMER Kinase Modulates Cell Cycle by Phosphorylating the MBF Repressor, Yox1, in Schizosaccharomyces pombe

open access: yesMycobiology, 2023
Lkh1, a LAMMER kinase homolog in the fission yeast Schizosaccharomyces pombe, acts as a negative regulator of filamentous growth and flocculation. It is also involved in the response to oxidative stress.
Kibum Park   +5 more
doaj   +1 more source

In Vitro Propagation and Phytochemical Composition of Centratherum punctatum Cass—A Medicinal Plant

open access: yesHorticulturae, 2023
An effective and reproducible micropropagation protocol was developed for Centratherum punctatum Cass. Successful in vitro initiation of callus and subsequent plant regeneration were obtained on nodal explants cultured on MS medium supplemented with ...
Anuradha Talan   +5 more
doaj   +1 more source

Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

open access: yesJournal of Translational Medicine, 2016
Background In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood.
María de Lourdes Mora-García   +10 more
doaj   +1 more source

Generalized, switch-like competitive heterodimerization networks [PDF]

open access: yes, 2007
High-dimensional switches have been proposed as a way to model cellular differentiation, particularly in the context of basic Helix-Loop-Helix (bHLH) competitive heterodimerization networks.
Cinquin, O, Page, KM
core   +1 more source

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