Results 31 to 40 of about 607,739 (256)
Cellular neurothekeoma with neuroendocrine differentiation
Dermatology Online Journal, 2011 We report a case of cellular neurothekeoma with unusual clinicopathological features in which neuroendocrine markers, determined by immunohistochemistry were observed. Histologically, the tumor showed a micronodular architecture with hypercellular lobules composed of slightly spindled to epithelioid cells, with nuclear atypia or pleomorphism and ...
D'Antonio A. +4 more
openaire +6 more sources
LncRNA HABON promoted liver cancer cells survival under hypoxia by inhibiting mPTP opening
Cell Death Discovery, 2022 Hypoxia is an important feature of the tumor microenvironment (TME). While targeting hypoxic TME is emerging as a potential strategy for treating solid tumors including liver cancer. Recent studies have shown that hypoxia can regulate tumor adaptation to
Lulu Wo +9 more
doaj +1 more source
Modeling DNA methylation dynamics with approaches from phylogenetics [PDF]
, 2014 Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation.
Capra, John A., Kostka, Dennis
core +1 more source
Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]
, 2017 Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen +7 more
core +2 more sources
Cell Death Discovery, 2022 Misalignment of physiological circadian rhythms promotes obesity which is characterized by white adipose tissue (WAT) expansion. Differentiation of Adipose stem/progenitor cells (ASCs) contributes to WAT increase but the importance of the cellular clock ...
Markus Mandl +14 more
doaj +1 more source
Role of FGFR2b expression and signaling in keratinocyte differentiation. Sequential involvement of PKCδ and PKCα [PDF]
, 2018 The tumor suppressor epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) induces human keratinocyte early differentiation. Moreover, protein kinases C (PKCs) are known to regulate the differentiation program in several cellular ...
Belleudi, Francesca +4 more
core +2 more sources
Differential Cellular Gene Expression in Ganglioglioma [PDF]
Epilepsia, 2007 Summary: Purpose: Gangliogliomas (GGs) are neuronal‐glial tumors highly associated with epilepsy. We hypothesized that the expression of select gene families including neurotransmitter receptor subunits and growth factors would be distinct in neurons and astrocytes within GG compared with adjacent cortex and that these changes would yield insights into
Samadani, Uzma +4 more
openaire +2 more sources
An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells
Stem Cell Reports, 2017 Summary: During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we
Yuta Koui +7 more
doaj +1 more source
Krüppel-like factors in cancer progression: three fingers on the steering wheel [PDF]
, 2013 Kruppel-like factors (KLFs) comprise a highly conserved family of zinc finger transcription factors, that are involved in a plethora of cellular processes, ranging from proliferation and apoptosis to differentiation, migration and pluripotency.
de Beeck, Ken Op +4 more
core +3 more sources
Cellular Acetylcholine Content and Neuronal Differentiation [PDF]
Journal of Neurochemistry, 1997 Abstract: N18TG2 neuroblastoma clone is defective for biosynthetic neurotransmitter enzymes; its inability to establish functional synapses is overcome in the neuroblastoma × glioma 108CC15, where acetylcholine synthesis is also activated. These observations suggest a possible relation between the ability to produce acetylcholine and the capability to ...
F. Bignami +6 more
openaire +5 more sources