Results 51 to 60 of about 607,739 (256)

Tissue-Specific Natural Synthesis of Galanthaminein Zephyranthes Species and Its Accumulation in Different In Vitro-Grown Organs Following Methyl Jasmonate Treatment

Plants
Galanthamine is an immensely valuable alkaloid exhibiting anti-cancer and antiviral activity. The cultivation of plant tissues in in vitro conditions is a good source for the synthesis and enrichment of secondary metabolites of commercial interest.
Rukaya Syeed, A. Mujib, Yashika Bansal, Mohammad Mohsin, Afeefa Nafees, Moien Qadir Malik, Jyoti Mamgain, Bushra Ejaz, Yaser Hassan Dewir, Katalin Magyar-Tábori   +9 more
doaj   +1 more source

Mechano-Chemical Effect of Gelatin- and HA-Based Hydrogels on Human Retinal Progenitor Cells

Gels, 2023
Engineering matrices for cell therapy requires design criteria that include the ability of these materials to support, protect and enhance cellular behavior in vivo.
Pierre C. Dromel, Deepti Singh, Alfredo Alexander-Katz, Motoichi Kurisawa, Myron Spector, Michael Young   +5 more
doaj   +1 more source

Enhanced differentiation of human embryonic stem cells towards definitive endoderm on ultrahigh aspect ratio nanopillars [PDF]

, 2015
Differentiation of human embryonic stem cells is widely studied as a potential unlimited source for cell replacement therapy to treat degenerative diseases such as diabetes.
Dufva, Martin, Gadegaard, Nikolaj, Hansson, Mattias, Holzmann Rasmussen, Camilla, McMeeking, Robert M., Petersen, Dorthe Roenn, Reynolds, Paul   +6 more
core   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Comparative Transcriptome Analysis of Non-Organogenic and Organogenic Tissues of Gaillardia pulchella Revealing Genes Regulating De Novo Shoot Organogenesis

Horticulturae
Gaillardia pulchella is an important plant species with pharmacological and ornamental applications. It contains a wide array of phytocompounds which play roles against diseases.
Yashika Bansal, A. Mujib, Mahima Bansal, Mohammad Mohsin, Afeefa Nafees, Yaser Hassan Dewir   +5 more
doaj   +1 more source

JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma. [PDF]

, 2016
A prominent mechanism of acquired resistance to BRAF inhibitors in BRAF (V600) -mutant melanoma is associated with the upregulation of receptor tyrosine kinases.
Atefi, Mohammad, Friedman, Michael, Graeber, Thomas G, Hong, Aayoung, Hugo, Willy, Komisopoulou, Evangelia, Kong, Xiangju, Le, Allison, Li, Richard, Lo, Roger S, Lomova, Anastasia, Moriceau, Gatien, Ribas, Antoni, Shi, Hubing, Song, Chunying, Ten Hoeve, Johanna, Titz, Bjoern   +16 more
core   +3 more sources

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses [PDF]

, 2020
The signalling pathways initiated by members of the transforming growth factor-β (TGFβ) family of cytokines control many metazoan cellular processes, including proliferation and differentiation, epithelial-mesenchymal transition (EMT) and apoptosis. TGFβ
A Rojas-Fernandez, A Woods, AR Ramjaun, AY Hsing, B Bierie, B Ozdamar, B-C Kim, BR Binder, C Allan, CJ David, CS Hill, DB Shackelford, EC Connolly, FA Ran, G Avery-Cooper, G Rena, G Rosti, GD Cuny, GJ Inman, GJ Inman, GM Keating, H Ikushima, J Massagué, J Massagué, J Massaous, J Ozanne, J Song, J Vogt, J Xu, JF Callahan, JL Wrana, JM Lizcano, Joan Massagué, JY Altarejos, K Clark, KA Brown, KJ Livak, LC Spender, LC Spender, M Abe, M Kowanetz, M Tojo, MO Li, MR Keeton, NJ Bright, P Lönn, PH Lin, PK Datta, PM Siegel, RJ Akhurst, RJ Akhurst, S DaCosta Byfield, S Dennler, S Edlund, S Strickson, SA Hawley, T Sonntag, TB Sundberg, Y Drabsch, Y Liu, Y Shi, Y Yang, Y Zhang, Y Zhang   +63 more
core   +2 more sources

Integrated GC-MS and UPLC-ESI-QTOF-MS based untargeted metabolomics analysis of in vitro raised tissues of Digitalis purpurea L

Frontiers in Plant Science
Digitalis purpurea L. is one of the important plant species of Nilgiris, Kashmir and Darjeeling regions of India, belonging to the family Plantaginaceae, with well-known pharmacological applications.
Yashika Bansal, A. Mujib, Jyoti Mamgain, Rukaya Syeed, Mohammad Mohsin, Afeefa Nafees, Yaser Hassan Dewir, Nóra Mendler-Drienyovszki   +7 more
doaj   +1 more source

Retinoblastoma Protein Paralogs and Tumor Suppression

Frontiers in Genetics, 2022
The retinoblastoma susceptibility gene (RB1) is the first tumor suppressor gene discovered and a prototype for understanding regulatory networks that function in opposition to oncogenic stimuli.
Mauricio Flores, David W. Goodrich
doaj   +1 more source

The effects of growth factors on multicellular spheroids formed by chick embryonic retinal cells [PDF]

, 1997
Retinal cells from chick embryos aged 7.5 days of gestation were cultured for two months in a non-adherent suspension culture dish to study the effects of growth factors and co-culture with retinal pigment epithelial cells on their differentiation ...
Matsuo, Nobuhiko, Matsuo, Toshihiko, Takabatake, Mayumi   +2 more
core   +1 more source