Results 71 to 80 of about 607,739 (256)

Hematopoietic Cytokine Gene Duplication in Zebrafish Erythroid and Myeloid Lineages

open access: yesFrontiers in Cell and Developmental Biology, 2018
Hematopoiesis is a precisely orchestrated process regulated by the activity of hematopoietic cytokines and their respective receptors. Due to an extra round of whole genome duplication during vertebrate evolution in teleost fish, zebrafish have two ...
Jana Oltova   +3 more
doaj   +1 more source

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

open access: yesFrontiers in Endocrinology, 2020
Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki   +16 more
doaj   +1 more source

Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis

open access: yes, 2000
Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''.
Furusawa, Chikara, Kaneko, Kunihiko
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A dynamical model of genetic networks describes cell differentiation [PDF]

open access: yes, 2010
Cell differentiation is a complex phenomenon whereby a stem cell becomes progressively more specialized and eventually gives rise to a specific cell type. Differentiation can be either stochastic or, when appropriate signals are present, it can be driven
Alessia Barbieri   +2 more
core   +1 more source

Protein S-palmitoylation in cellular differentiation [PDF]

open access: yesBiochemical Society Transactions, 2017
Reversible protein S-palmitoylation confers spatiotemporal control of protein function by modulating protein stability, trafficking and activity, as well as protein–protein and membrane–protein associations. Enabled by technological advances, global studies revealed S-palmitoylation to be an important and pervasive posttranslational modification in ...
Zhang, Mingzi M., Hang, Howard C.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina

open access: yesThe Scientific World Journal, 2013
Orchestrated proliferation, differentiation, and cell death contribute to the generation of the complex cytoarchitecture of the central nervous system, including that of the neuroretina.
Teresa Chavarría   +4 more
doaj   +1 more source

Relatedness and the evolution of mechanisms to divide labor in microorganisms

open access: yesEcology and Evolution, 2021
Division of labor occurs when cooperating individuals specialize to perform different tasks. In bacteria and other microorganisms, some species divide labor by random specialization, where an individual's role is determined by random fluctuations in ...
Ming Liu   +2 more
doaj   +1 more source

Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. [PDF]

open access: yes, 2018
Cellular differentiation involves remodeling cellular architecture to transform one cell type to another. By investigating mitochondrial dynamics during meiotic differentiation in budding yeast, we sought to understand how organelle morphogenesis is ...
Berchowitz, Luke   +5 more
core   +2 more sources

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