Results 91 to 100 of about 4,741,341 (392)
miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation [PDF]
, 2018 Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this particular lineage, more effort is still required to stress the importance of developing an efficient, reproducible, easy, and cost ...
Aguilera, Yolanda +8 more
core +1 more source
Spatial restriction of cellular differentiation. [PDF]
Genes & Development, 1993 Myxococcus xanthus cells differentiate into myxospores within a fruiting body, an aggregate of approximately 10(5) cells. Previous work had discerned an inner and outer domain within the fruiting body differentiated by cell density and cell alignment. To test whether the two domains might play different roles in spore differentiation, developmentally ...
Dale Kaiser, Brian Sager
openaire +3 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina
The Scientific World Journal, 2013 Orchestrated proliferation, differentiation, and cell death contribute to the generation of the complex cytoarchitecture of the central nervous system, including that of the neuroretina.
Teresa Chavarría +4 more
doaj +1 more source
Frontiers in Endocrinology, 2020 Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki +16 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Mesenchymal stem/stromal cells (MSCs) are promising cell sources for regenerative medicine and the treatment of autoimmune disorders. Comparing MSCs from different tissues at the single-cell level is fundamental for optimizing clinical applications. Here
Wenhong Hou +10 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Gut MicrobesThe majority of cohort-specific studies associating gut microbiota with obesity are often contradictory; thus, the replicability of the signature remains questionable.
Deep Chanda, Debojyoti De
doaj +1 more source
Hematopoietic Cytokine Gene Duplication in Zebrafish Erythroid and Myeloid Lineages
Frontiers in Cell and Developmental Biology, 2018 Hematopoiesis is a precisely orchestrated process regulated by the activity of hematopoietic cytokines and their respective receptors. Due to an extra round of whole genome duplication during vertebrate evolution in teleost fish, zebrafish have two ...
Jana Oltova +3 more
doaj +1 more source
Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis
, 2000 Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''.
Furusawa, Chikara, Kaneko, Kunihiko
core +3 more sources