Results 91 to 100 of about 1,459,173 (350)

Serum carcinoembryonic antigen tends to decrease in poorly-differentiated colorectal cancer

open access: yesUniversa Medicina, 2015
BACKGROUND Carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 are tumor markers for colorectal cancer (CRC), both having prognostic value.
Ester Morina Silalahi   +2 more
doaj   +1 more source

PLLA/ZnO nanocomposites: dynamic surfaces to harness cell differentiation [PDF]

open access: yes, 2016
This work investigates the effect of the sequential availability of ZnO nanoparticles, (nanorods of ∼40 nm) loaded within a degradable poly(lactic acid) (PLLA) matrix, in cell differentiation.
Lizundia, Erlantz   +3 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Cell-Type Specific Metabolic Flux Analysis: A Challenge for Metabolic Phenotyping and a Potential Solution in Plants

open access: yesMetabolites, 2017
Stable isotope labelling experiments are used routinely in metabolic flux analysis (MFA) to determine the metabolic phenotype of cells and tissues.
Merja T. Rossi   +4 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Modelling acute myeloid leukaemia in a continuum of differentiation states

open access: yesLetters in Biomathematics, 2018
Here we present a mathematical model of movement in an abstract space representing states of cellular differentiation. We motivate this work with recent examples that demonstrate a continuum of cellular differentiation using single-cell RNA-sequencing ...
H. Cho   +6 more
doaj   +1 more source

Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells [PDF]

open access: yes, 2014
© 2015 Macmillan Publishers Limited. All rights reserved. microRNA-34a (miR-34a) and sirtuin 1 (SirT1) have been extensively studied in tumour biology and longevityaging, but little is known about their functional roles in smooth muscle cell (SMC ...
A Margariti   +55 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

The proteome of the heterocyst cell wall in Anabaena sp. PCC 7120 [PDF]

open access: yes, 2007
Anabaena sp. PCC 7120 is a filamentous cyanobacterium that serves as a model to analyze prokaryotic cell differentiation, evolutionary development of plastids, and the regulation of nitrogen fixation.
Berg, Matthias   +8 more
core   +1 more source

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