Results 121 to 130 of about 4,741,341 (392)

The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts [PDF]

, 2013
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response.
A Fotovati, A Karaczyn, B Chen, B Xu, Baosheng Chen, CR Roh, D Pflueger, D Piquemal, DM Byers, DM Nelson, E Alsat, E Shaw, EA Mostaghel, Eric Y. Chuang, EU Jung, HJ Kliman, J Hwang, Jacob C. Larkin, JF Mouillet, JR Hickok, K Hirata, K Kokame, K Ogata, KJ Livak, KT Kim, L Aravind, L Kalaydjieva, LW Donaldson, M Hunter, M Hunter, MA Zoroddu, N van Belzen, NT Le, O Genbacev, P Lachat, RB Donker, RH King, RK Riemer, RP Caruso, S Bandyopadhyay, S Chen, S Sibold, S Smith, S Stein, SJ Choi, SK Kachhap, SK Kurdistani, T Fujii, T Matsugaki, T Mishima, T Okuda, T Sugiki, TM Lin, V Melotte, VM Banz, W Ulrix, WT Schaiff, X Qu, X Xu, Xiao-Hua Shi, Y Sadovsky, Y Sadovsky, Y Song, Y Taketomi, Y Zhou, Yoel Sadovsky, Z Chen, Z Kovacevic   +67 more
core   +4 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Positional plasticity in regenerating Amybstoma mexicanum limbs is associated with cell proliferation and pathways of cellular differentiation

BMC Developmental Biology, 2015
The endogenous ability to dedifferentiate, re-pattern, and re-differentiate adult cells to repair or replace damaged or missing structures is exclusive to only a few tetrapod species.
Catherine D. McCusker, Antony T. Athippozhy, Carlos Díaz-Castillo, Charless C. Fowlkes, D. Gardiner, S. Voss   +5 more
semanticscholar   +1 more source

VSX1 EXPRESSION INITIALLY DESCRIBED IN THE V2 SPINAL INTERNEURON PRECURSOR CELLS IS ALSO PRESENT IN THE ADULT SPINAL CORD AND MAINTAINED AFTER A TRAUMATIC INJURY

IBRO Neuroscience Reports, 2023
Ana Dominguez-Bajo, Andrea Angla, Guillaume Van Lint, Stéphanie Debrulle, Frédéric Clotman   +4 more
doaj   +1 more source

Lineage dynamics of murine pancreatic development at single-cell resolution. [PDF]

, 2018
Organogenesis requires the complex interactions of multiple cell lineages that coordinate their expansion, differentiation, and maturation over time.
Byrnes, Lauren E, Gilchrist, Caroline L, Knox, Sarah M, Meyer, Nathaniel P, Sneddon, Julie B, Subramaniam, Meena, Tward, Aaron D, Wong, Daniel M, Ye, Chun J   +8 more
core   +2 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Modelling acute myeloid leukaemia in a continuum of differentiation states

Letters in Biomathematics, 2018
Here we present a mathematical model of movement in an abstract space representing states of cellular differentiation. We motivate this work with recent examples that demonstrate a continuum of cellular differentiation using single-cell RNA-sequencing ...
H. Cho, K. Ayers, L. de Pills, Y.-H. Kuo, J. Park, A. Radunskaya, R. C. Rockne   +6 more
doaj   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Biofilms formed by the archaeon Haloferax volcanii exhibit cellular differentiation and social motility, and facilitate horizontal gene transfer

BMC Biology, 2014
BackgroundArchaea share a similar microbial lifestyle with bacteria, and not surprisingly then, also exist within matrix-enclosed communities known as biofilms.
Scott Chimileski, Michael J Franklin, R. Papke   +2 more
semanticscholar   +1 more source

Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]

, 2016
Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG, Cocchi, E, de la Torre-Ubieta, L, Freitag, CM, Fulda, S, Geschwind, DH, Haslinger, D, Lindlar, S, Rothämel, T, Stein, JL, Waltes, R   +10 more
core   +1 more source