Results 201 to 210 of about 1,498,984 (353)

A segmentation clock patterns cellular differentiation in a bacterial biofilm. [PDF]

Cell, 2022
Chou KT, Lee DD, Chiou JG, Galera-Laporta L, Ly S, Garcia-Ojalvo J, Süel GM.   +6 more
europepmc   +1 more source

Photosynthetic Gene Expression and Cellular Differentiation in Developing Maize Leaves [PDF]

, 1985
Belinda Martineau, William C. Taylor
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comparative Network Biology Discovers Protein Complexes That Underline Cellular Differentiation in Anabaena sp. [PDF]

Mol Cell Proteomics, 2022
Xu C, Wang B, Heng H, Huang J, Wan C.
europepmc   +1 more source

The Relationship of Cellular Differentiation to Colonial Morphogenesis of the Blue-green Alga, Nostoc muscorumA

, 1964
Norman Lazaroff, Wolf Vishniac
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Nuclear envelope and chromatin choreography direct cellular differentiation. [PDF]

Nucleus
Nair A, Khanna J, Kler J, Ragesh R, Sengupta K.   +4 more
europepmc   +1 more source

Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. [PDF]

Nat Commun, 2023
Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury SR, Morrison LC, Fresnoza A, Zagozewski J, Venugopal C, Anderson CM, Singh SK, Banerji V, Werbowetski-Ogilvie TE, Sharif T.   +13 more
europepmc   +1 more source

Differential requirements for cellular enhancers in stem and differentiated cells [PDF]

, 1988
Thomas Vogt, Reid S. Compton, Richard Scott, Shirley M. Tilghman   +3 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source